Results 71 to 80 of about 57,782 (265)
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Digital archives, cultural identity and diversity, meaning economy . Some general ideas.
In this short speech, I develop some general ideas concerning possible evolutions of digital archives in relation, on the one hand, to cultural identity and diversity and, on the other hand, to what sometimes is called a "meaning economy".
openaire +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
SPACE, CULTURE AND IDENTITY: SOCIAL MEANING OF SPACE AMONG ISPARTA TAHTACIS
The problems encountered in today's urban spaces by Tahtacis, who are one of the major building blocks of Anatolian culture, constitute a significant field of discussion.
Suat KOLUKIRIK
doaj
Asem, Sawo, Kelapa, dan Masyarakat Kota Serang
Representation of community identity can be displayed through the diversity of culture and traditions. The result of a growing culture one of which is the culinary community. Representation identity is shown through herbs and materials used in processing.
Diana Tustiantina
doaj +1 more source
Precarity, Identity, and the Meaning of Cultural and Creative Work
AbstractThis chapter focuses on the subjective experiences of precarity as these were relayed to us and discussed during the research. In doing so, the chapter explores the significance of a number of existential themes relating to identity, vulnerability, and the desire for recognition that impacted on freelance and self-employed live performers ...
Philip Hancock, Melissa Tyler
openaire +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source

