Results 71 to 80 of about 7,509,795 (332)

RSL24D1 sustains steady-state ribosome biogenesis and pluripotency translational programs in embryonic stem cells

Nature Communications, 2023
Pluripotency is coordinated at multiple levels of gene expression. Here the authors show that ribosome biogenesis is tightly regulated in embryonic stem cells (ESC) to control the translation of transcription and chromatin factors and dictate ESC fate.
Sébastien Durand, Marion Bruelle, Fleur Bourdelais, Bigitha Bennychen, Juliana Blin-Gonthier, Caroline Isaac, Aurélia Huyghe, Sylvie Martel, Antoine Seyve, Christophe Vanbelle, Annie Adrait, Yohann Couté, David Meyronet, Frédéric Catez, Jean-Jacques Diaz, Fabrice Lavial, Emiliano P. Ricci, François Ducray, Mathieu Gabut   +18 more
doaj   +1 more source

Optimal experience and personal growth. Flow and the consolidation of place identity [PDF]

, 2016
This study examined the relationship between flow experience and place identity, based on eudaimonistic identity theory (EIT) which prioritizes self-defining activities as important for an individual's identification of his/her goals, values, beliefs ...
Aristotle, Barber, Bonaiuto, Bonaiuto, Bonaiuto, Bonaiuto, Bonnes, Bonnes, Brislin, Coatsworth, Coatsworth, Cooper, Craig, Csikszentmihalyi, Csikszentmihalyi, Csikszentmihalyi, Csikszentmihalyi, Csikszentmihalyi, Csikszentmihalyi, Csikszentmihalyi, Csikszentmihalyi, Csikszentmihalyi, Csikszentmihalyi, Davidson, Deci, Deci, Deci, Deci, Delle Fave, Delle Fave, Demerouti, Diener, Dimitrakopoulou, Dixon, Eccles, Erikson, Erikson, Fornara, Fraser, Fredricks, Giuliani, Giuliani, Hamari, Hansen, Harari, Harmison, Hernández, Huta, Irwin, Jackson, Jorgensen, Kowal, Kyle, Kyle, Kyle, Kyle, Lee, Mao, Mao, Martin, Maslow, Massimini, Nakamura, Nakamura, Nielsen, Norton, OECD, Prezza, Prezza, Proshansky, Proshansky, Proshansky, Ross, Russell, Ryff, Ryff, Schwartz, Schwartz, Seligman, Sharp, Skadberg, Stedman, Tietze, Twigger-Ross, Waterman, Waterman, Waterman, Waterman, Waterman, Waterman, Waterman, Waterman, Waterman, Waterman, Waterman, Williams, Wöran   +96 more
core   +2 more sources

Human-centered design of a privacy assistant and its impact on perceived transparency and intervenability

i-com
This paper showcases a user study on users’ preferences and perceptions of data protection (e.g., intervenability and transparency) in a privacy assistant application.
Kiss Lennart, Sellung Rachelle
doaj   +1 more source

Implementing Health‐Related Quality of Life Assessment in Pediatric Oncology: A Feasibility Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background There is growing interest in embedding health‐related quality of life (HRQoL) assessment and patient‐reported outcome measures (PROMs) within clinical cancer care. This study evaluated the feasibility, acceptability, and usability of implementing an electronic PROM (ePROM) platform to measure HRQoL in children with cancer ...
Mikaela Doig, Sophie Jessop, Jordan R. Hansford, Hien Le, Matthew O'Connor, Peter Gorayski, Andrew Cunningham, Amanda Hutchinson, Victoria Bedford, Eva Bezak, Nayana Parange, Kelly Skelton, Timothy Price, Michala Short   +13 more
wiley   +1 more source

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa, Daisuke Honda, Seigo Akari, Tadao Akizawa   +3 more
wiley   +1 more source

Identity and interaction: a sociocultural linguistic approach

Discourse Studies, 2005
The article proposes a framework for the analysis of identity as produced in linguistic interaction, based on the following principles: (1) identity is the product rather than the source of linguistic and other semiotic practices and therefore is a ...
Mary Bucholtz, Kira Hall
semanticscholar   +1 more source

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda, Tomohiro Saito, Masahide Mizobuchi, Tomoki Shimomura, Saki Kawamori, Mitsuru Kawanishi, Natsuko Hattori, Jo Sugiyama, Satoshi Tsubata, Hanami Horiguchi, Kazuki Abe, Nao Iida, Yuki Kajio, Nao Oguro, Ryo Yanai, Hirokazu Honda   +15 more
wiley   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Molecular and epistatic interactions between pioneer transcription factors shape nucleosome dynamics and cell differentiation

Nature Communications
Pioneer transcription factors (TF) bind nucleosome-embedded DNA motifs to activate new regulatory elements and promote differentiation. However, the complexity, binding dependencies and temporal effects of their action remain unclear.
Rémi-Xavier Coux, Agnès Dubois, Almira Chervova, Inma Gonzalez, Sandrine Vandormael-Pournin, Michel Cohen-Tannoudji, Pablo Navarro   +6 more
doaj   +1 more source

Trade-off hacking: Have the cake and eat it too? Turning competing interests into win-wins in data-driven food technology [version 2; peer review: 1 approved, 2 approved with reservations]

Open Research Europe
Data-driven innovations in the food sector, from personalised nutrition to supply chain tracking, promise clear benefits but introduce complex trade-offs between competing interests such as personalisation and privacy, or performance and explainability ...
Ferdinand Ferroli
doaj   +1 more source