Results 71 to 80 of about 303,359 (251)

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

The Pervasiveness of Digital Identity: Surveying Themes, Trends, and Ontological Foundations

Information
Digital identity operates as the connective infrastructure of the digital age, linking individuals, organisations, and devices into networks through which services, rights, and responsibilities are transacted.
Matthew Comb, Andrew Martin
doaj   +1 more source

Privacy-aware blockchain for personal data sharing and tracking

Open Computer Science, 2019
Secure data distribution is critical for data accountability. Surveillance caused privacy breaching incidents have already questioned existing personal data collection techniques.
Onik Md Mehedi Hassan, Kim Chul-Soo, Lee Nam-Yong, Yang Jinhong   +3 more
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Systematic Artefact-Based Review of Government Digital Identity Programmes: Alignment, Maturity and Transparency

Journal of Cybersecurity and Privacy
Digital identity is increasingly treated as foundational infrastructure for digital economies and public services, yet national approaches remain fragmented and difficult to compare. This study presents a PRISMA-guided systematic artefact-based review of
Matthew Comb, Andrew Martin
doaj   +1 more source

Identity Management

, 2017
PCC Task Group on Identity Management in NACO members:John Riemer, chair - University of California Los Angeles (UCLA)Amber Billey - Columbia UniversityMichelle Durocher, PoCo representative - Harvard UniversityPaul Frank, PCC NACO - Library of CongressStephen Hearn - University of MinnesotaVioleta Ilik - Northwestern University Feinberg School of ...
Ilik, Violeta, Durocher, Michelle, Frank, Paul, Riemer, John, Billey, Amber, Hearn, Stephen, Liss, Jennifer, MacEwan, Andrew, Stalberg, Erin   +8 more
openaire   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source