Results 61 to 70 of about 344,308 (202)

A PRSZT Registry Analysis of Prognostic Factors Influencing Survival and Relapse Rates After Second Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT A second allogeneic (allo‐)hematopoietic stem cell transplantation (HSCT2) is a potential curative option for pediatric patients with acute lymphoblastic leukemia (ALL) following relapse after first allogeneic transplantation (HSCT1), but its efficacy is limited by high relapse rates and transplant‐related toxicity in highly pretreated ...
Ava Momm   +10 more
wiley   +1 more source

Enhancing STEM outcomes through mentorship (Mis)matching: an identity grafting approach

open access: yesInternational Journal of STEM Education
Background As mentorship programs variably impact STEM identity formation, significant attention is paid to whether mentors and mentees are well-matched.
Daphnee Hui Lin Lee   +4 more
doaj   +1 more source

Spaced seeds improve k-mer-based metagenomic classification [PDF]

open access: yes, 2015
Metagenomics is a powerful approach to study genetic content of environmental samples that has been strongly promoted by NGS technologies. To cope with massive data involved in modern metagenomic projects, recent tools [4, 39] rely on the analysis of k ...
Brinda, Karel   +2 more
core   +2 more sources

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

PGCA: An algorithm to link protein groups created from MS/MS data. [PDF]

open access: yesPLoS ONE, 2017
The quantitation of proteins using shotgun proteomics has gained popularity in the last decades, simplifying sample handling procedures, removing extensive protein separation steps and achieving a relatively high throughput readout.
David Kepplinger   +8 more
doaj   +1 more source

Are family firms good employers? [PDF]

open access: yes, 2018
Family firms employ about 60 percent of the global workforce. While it is widely assumed that they are good employers, data about their conduct is mixed.
Neckebrouck, Jeroen   +2 more
core   +2 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

THE ROLE OF PHYSICAL IDENTITY OF THE SAMPLE AND CORRECT COMPARISON STIMULUS IN MATCHING‐TO‐SAMPLE PARADIGMS1 [PDF]

open access: yesJournal of the Experimental Analysis of Behavior, 1978
Pigeons were trained in a higher‐order conditional discrimination paradigm to assess the role of physical identity in a within‐subjects design. A line orientation which was superimposed on all response keys signalled whether a response to the matching color or a response to the nonmatching color was correct.
openaire   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Face Deidentification with Generative Deep Neural Networks

open access: yes, 2017
Face deidentification is an active topic amongst privacy and security researchers. Early deidentification methods relying on image blurring or pixelization were replaced in recent years with techniques based on formal anonymity models that provide ...
Ekenel, Hazım Kemal   +5 more
core   +1 more source

Home - About - Disclaimer - Privacy