Results 61 to 70 of about 344,308 (202)
ABSTRACT A second allogeneic (allo‐)hematopoietic stem cell transplantation (HSCT2) is a potential curative option for pediatric patients with acute lymphoblastic leukemia (ALL) following relapse after first allogeneic transplantation (HSCT1), but its efficacy is limited by high relapse rates and transplant‐related toxicity in highly pretreated ...
Ava Momm +10 more
wiley +1 more source
Enhancing STEM outcomes through mentorship (Mis)matching: an identity grafting approach
Background As mentorship programs variably impact STEM identity formation, significant attention is paid to whether mentors and mentees are well-matched.
Daphnee Hui Lin Lee +4 more
doaj +1 more source
Spaced seeds improve k-mer-based metagenomic classification [PDF]
Metagenomics is a powerful approach to study genetic content of environmental samples that has been strongly promoted by NGS technologies. To cope with massive data involved in modern metagenomic projects, recent tools [4, 39] rely on the analysis of k ...
Brinda, Karel +2 more
core +2 more sources
Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
PGCA: An algorithm to link protein groups created from MS/MS data. [PDF]
The quantitation of proteins using shotgun proteomics has gained popularity in the last decades, simplifying sample handling procedures, removing extensive protein separation steps and achieving a relatively high throughput readout.
David Kepplinger +8 more
doaj +1 more source
Are family firms good employers? [PDF]
Family firms employ about 60 percent of the global workforce. While it is widely assumed that they are good employers, data about their conduct is mixed.
Neckebrouck, Jeroen +2 more
core +2 more sources
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
THE ROLE OF PHYSICAL IDENTITY OF THE SAMPLE AND CORRECT COMPARISON STIMULUS IN MATCHING‐TO‐SAMPLE PARADIGMS1 [PDF]
Pigeons were trained in a higher‐order conditional discrimination paradigm to assess the role of physical identity in a within‐subjects design. A line orientation which was superimposed on all response keys signalled whether a response to the matching color or a response to the nonmatching color was correct.
openaire +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Face Deidentification with Generative Deep Neural Networks
Face deidentification is an active topic amongst privacy and security researchers. Early deidentification methods relying on image blurring or pixelization were replaced in recent years with techniques based on formal anonymity models that provide ...
Ekenel, Hazım Kemal +5 more
core +1 more source

