Results 81 to 90 of about 2,716,323 (287)

Gravity‐Dependent Modulation of Downbeat Nystagmus: Insights From Velocity‐Storage Dysfunction

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Downbeat nystagmus varies with head position, a phenomenon termed gravity‐dependent modulation. We aimed to clarify its mechanism using a velocity‐storage model. Methods In 10 patients with downbeat nystagmus due to cerebellar disorders, we recorded eye movements at different pitch‐ and roll‐axis head positions.
Ji‐Hyung Park   +5 more
wiley   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem   +9 more
wiley   +1 more source

Sarah Hammerschlag, The Figural Jew: Politics and Identity in Postwar French Thought [PDF]

open access: yes, 2016
Review of Sarah Hammerschlag, The Figural Jew: Politics and Identity in Postwar French Thought, Chicago, University of Chicago Press ...
Landy, F
core   +1 more source

Advisory content in politics: the form of mitigation of the negative impact of identity politics on Instagram account @lensamu and @nuonline_id

open access: yesJournal of Social Studies
This article aims to analyze efforts to mitigate the negative impacts of identity politics by two large mass organizations in Indonesia, Muhammadiyah and Nahdhatul Ulama (NU), through their Instagram accounts.
Fuandani Istiati   +1 more
doaj   +1 more source

Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay   +15 more
wiley   +1 more source

A politics of place framework for unravelling peri-urban conflict: An example of peri-urban Sydney, Australia

open access: yesJournal of Urban Management, 2018
Peri-urban areas are increasingly described as ‘third’ spaces with unique characteristics, in opposition to spaces awaiting urban development. However, in many peri-urban areas the process of defining what this ‘third’ space is, is triggering conflict ...
Laure-Elise Ruoso, Roel Plant
doaj   +1 more source

The Price of Precision: A Critical Review of Molecular Diagnostics in Glioma, From Guidelines to Global Disparities

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Gliomas have undergone a profound redefinition over the past decade, transitioning from morphology‐based entities to biologically coherent diseases defined by molecular alterations. The 2021 WHO Classification of Tumors of the Central Nervous System and its 2022 update formalize this shift, establishing integrated diagnosis as the global ...
Maria Guarnaccia, Sebastiano Cavallaro
wiley   +1 more source

Identity Processes in Adulthood: Diverging Domains

open access: yes, 2015
Patterns of identity formation were analyzed in a longitudinal framework, from ages 27 to 36 and then to 42 years of age. Information from all 3 ages was available for 197 participants (100 women, 97 men). A variation of Marcia’s (1966) Identity Status
Kokko, Katja   +2 more
core   +1 more source

Defects of democracy: The continuity of identity politics in post-reform regional elections

open access: yesJurnal Sosiologi Dialektika
Identity politics in Indonesia is more closely related to issues of race, religion, ideology and local interests than other issues. This research aims to determine the impact of identity politics in every regional election (pilkada) in Indonesia.
Agus Danugroho
doaj   +1 more source

White Matter and Perivascular Imaging Changes in Alzheimer's Disease and Cerebral Amyloid Angiopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peak‐width of skeletonized mean diffusivity (PSMD) and diffusion tensor imaging–analysis along the perivascular space (DTI‐ALPS), reflecting white matter integrity and glymphatic function, are altered in Alzheimer's disease (AD).
Debina Laishram   +3 more
wiley   +1 more source

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