Results 51 to 60 of about 1,388 (174)

The Impact of Treatment Method and Timing on the Long Term Outcomes of Pediatric Clubfoot Management

Foot & Ankle Orthopaedics, 2022
Category: Other; Ankle; Hindfoot; Midfoot/Forefoot Introduction/Purpose: The Ponseti method of serial casting has been widely accepted as the new gold standard for management of idiopathic clubfoot, replacing joint invasive surgery, once the method-of ...
Julia Nguyen BS, Jacob Veliky BS, Aedan Hanna, Jae Hoon Choi, Dhvani Shihora, Aleksandra McGrath, Neil Kaushal, Folorunsho Edobor-Osula MD, Alice Chu   +8 more
doaj   +1 more source

Sequential prenatal diagnosis of fetal skeletal dysplasia: A cohort study

Acta Obstetricia et Gynecologica Scandinavica, Volume 104, Issue 5, Page 860-874, May 2025.
Of the 147 SD fetuses, 58 cases with negative CMA results underwent WES, and 21 genes with pathogenic/likely pathogenic variants were detected in 21 cases, including FGFR3 (n = 11), COL1A1 (n = 2), COL1A2 (n = 1), RUNX2 (n = 1), COL2A1 (n = 1), LMX1B (n = 1), GLI3 (n = 1), DYNC2H1 (n = 1), ALPL (n = 1), and SHOX (n = 1).
Mengting Jiang, Bin Zhang, Jing Wang, Wei Qiao, Xiuzhen Mao, Bin Yu   +5 more
wiley   +1 more source

Phosphoinositide Metabolism: Biochemistry, Physiology and Genetic Disorders

Journal of Inherited Metabolic Disease, Volume 48, Issue 2, March 2025.
ABSTRACT Phosphatidylinositol, a glycerophospholipid with a myo‐inositol head group, can form seven different phosphoinositides (PItds) by phosphorylation at inositol carbons 3, 4 and/or 5. Over 50 kinases and phosphatases participate in PItd metabolism, creating an interconnected PItd network that allows for precise temporal and spatial regulation of ...
Francis Rossignol, Foudil Lamari, Grant A. Mitchell   +2 more
wiley   +1 more source

The Ponseti Method for the Treatment of Clubfeet Associated with Down Syndrome

Foot & Ankle Orthopaedics, 2022
Category: Other Introduction/Purpose: This study aims to compare treatment characteristics and outcomes of clubfoot patients with Down Syndrome (DS) to those with idiopathic clubfoot treated with the Ponseti method.
Edwin Portalatin, Sarah Parenti, Jordan L. Polk, Chan-Hee Jo, Jacob R. Zide MD, Anthony Riccio   +5 more
doaj   +1 more source

Can We Improve Our Routine Urological Assessment to Exclude Neurogenic Causes for Lower Urinary Tract Dysfunction? ICI‐RS 2024

Neurourology and Urodynamics, Volume 44, Issue 3, Page 609-615, March 2025.
ABSTRACT Aims After presentation with urinary symptoms, an underlying neurological mechanism sometimes emerges subsequently. Increased awareness may bring earlier diagnosis, improving prognosis and outcomes. Methods A 2024 International Consultation on Incontinence Research Society think‐tank considered the clinical pathway for identification of an ...
Marcus J. Drake, Salvador Arlandis, Marcio A. Averbeck, Enrico Finazzi Agrò, Claire Hentzen, Giovanni Mosiello, Jalesh Panicker, Matthew Smith, Katie Webb   +8 more
wiley   +1 more source

Analysis of a Series of 26 Cases With Prenatal Skeletal Dysplasia via Multiplatform Genetic Detection

Molecular Genetics &Genomic Medicine, Volume 13, Issue 1, January 2025.
ABSTRACT Background Skeletal dysplasia (SD) represents a series of highly heterogeneous congenital genetic diseases affecting the human skeletal system. Refined genetic diagnosis is helpful for the accurate diagnosis and prognosis evaluation of SDs.
Li‐min Cui, Hua‐ying Hu, Xiao‐mei Zhai, Ming‐fei Qi, Yan‐ming Liu, Cong‐ying Han, Jing Zhang, Ming Shen, Yu‐lan Xiang, Wen‐qi Chen, Kai Yang, Dong‐liang Zhang, Huan‐xia Xing   +12 more
wiley   +1 more source

Anesthetic Challenges of Caring for an Adult With Moebius Syndrome: A Case Report

Case Reports in Anesthesiology, Volume 2025, Issue 1, 2025.
Background Moebius syndrome (MBS) is a rare congenital disorder with facial nerve palsies and craniofacial malformations, increasing the risk of a difficult airway during anesthesia. We report a difficult airway in an adult with MBS during an elective procedure, which is unique as most reports of MBS are in children. Case Presentation Our patient was a
Geetasravya Vegunta, Giovanna Patafio, Swata Gade, Kwame Awuku, Evelyne Kalyoussef, Shridevi Pandya Shah, Shashank Kaushik   +6 more
wiley   +1 more source

Treatment of the idiopathic and complex congenital talipes equinovarus with Ponseti method

Zdravniški Vestnik, 2015
:Congenital idiopathic clubfoot is a deformity typically occurring in an otherwise healthy child which occurs in 11,4 in 10.000 live births. Approximately one-half of cases present with bilateral deformity and affects boys and girls equally.
Lovro Suhodolčan, Karin Schara, Janez Brecelj, Vane Antolič   +3 more
doaj  

Motor ability in children treated for idiopathic clubfoot. A controlled pilot study

BMC Pediatrics, 2009
Background To study motor ability at seven years of age in children treated for idiopathic clubfoot and its relation to clubfoot laterality, foot status and the amount of surgery performed. Methods Twenty children (mean age 7.5 years, SD 3.2 months) from
Westbom Lena, Andriesse Hanneke, Hägglund Gunnar   +2 more
doaj   +1 more source

Complex skeletal foot malformation in a Samnite “warrior grave” from Abruzzo, southern Italy (8th–5th century BCE)

International Journal of Osteoarchaeology, Volume 34, Issue 6, November/December 2024.
Abstract This report describes a male skeleton recovered from the Samnite necropolis of Barrea (Abruzzo, 8th–5th century BCE), showing one malformed foot consistent with the diagnosis of unilateral congenital clubfoot associated with tarsal and tarsometatarsal coalitions in the same foot.
Stefania Luciani
wiley   +1 more source