Myeloid A20 Regulates Periodontal Tissue Integrity and Temporomandibular Joint Structure
Journal of Periodontal Research, Volume 61, Issue 8, Page 944-954, August 2026.Dysregulation of A20 signaling has been implicated in several immune‐mediated diseases, including rheumatoid arthritis and psoriasis, conditions characterized by excessive NF‐κB activation and inflammatory tissue damage. The structural alterations observed in this model suggest that impaired regulation of innate immune signaling may increase ...
Karol Alí Apaza Alccayhuaman +6 more
wiley +1 more source
The Autosomal Recessive Inheritance of Hereditary Gingival Fibromatosis
Case Reports in Dentistry, 2013 Hereditary gingival fibromatosis (HGF) is a rare condition which is marked by enlargement of gingival tissue that covers teeth to various extents leading to aesthetic disfigurement.
Poulami Majumder +4 more
doaj +1 more source
A Central Somatic Transmission Mediates Proprioceptive Facilitation of Muscle Pain
Advanced Science, Volume 13, Issue 34, 19 June 2026.Zhang et al. uncover a novel central mechanism for persistent muscle pain, in which TRPA1 sensitization in MeV proprioceptive neurons enhances somatic secretion. This, in turn, disinhibits descending pain control from neighboring noradrenergic locus coeruleus neurons via local GABAergic circuits, thereby promoting inflammatory muscle pain.
Xiaoyu Zhang +15 more
wiley +1 more source
Sodium valproate induced gingival enlargement with pre-existing chronic periodontitis
, 2012 Gingival enlargement is a common clinical feature of gingival and periodontal diseases. Currently, more than 20 prescription medications are associated with gingival enlargement.
Vaibhavi Joshipura
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Nifedipine-induced gingival enlargement: Correlation with dose and oral hygiene
, 2012 Gingival enlargement is a common finding in a routine dental practice. Though it has many etiological factors, enlargement due to drugs which are administered to treat the systemic problems is of major concern which needs attention.
Issac Joseph +3 more
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Leptin and Pro-Inflammatory Stimuli Synergistically Upregulate MMP-1 and MMP-3 Secretion in Human Gingival Fibroblasts [PDF]
, 2016 Introduction Gingival fibroblast-mediated extracellular matrix remodelling is implicated in the pathogenesis of periodontitis, yet the stimuli that regulate this response are not fully understood. The immunoregulatory adipokine leptin is detectable in
Andrew J Skelton +28 more
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Gingival Enlargement in Antihypertensive Medication
, 2009 Introduction: Drug-induced gingival enlargement is a well documented side effect with the use of phenytoin, cyclosporine and calcium channel blockers. The prevalence of gingival enlargement induced by calcium channel blockers is uncertain.
P Mishra, Shaili Pradhan
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Drug-induced gingival enlargement: Series of cases [PDF]
, 2017 Introduction: Gingival enlargement (GA) is a benign condition of the oral cavity that is characterized by the excessive growth of the gingiva in mass and volume.
Isabella Manzur-Villalobos +7 more
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The management of gingival hyperplasia on patient with orthodontic treatment [PDF]
, 2013 Recently the orthodontic treatment needs had increased with the increased of community incomes. During treatment sometimes there is problem toward periodontal tissue.
Hasanuddin
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Gingival enlargement in children treated with antiepileptics
, 2004 This study was conducted to determine the occurrence, severity, and risk factors of gingival enlargement in children treated with valproate and other nonvalproate antiepileptic drugs. A cross-sectional study was carried out in which data obtained from 68
Tan, HY, Gurbuz, T, Dagsuyu, IM
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