Results 71 to 80 of about 43,880 (267)

Familial autoimmunity in patients with idiopathic inflammatory myopathies

Journal of Internal Medicine, 2022
Familial associations can be indicators of shared genetic susceptibility between two diseases. Previous data on familial autoimmunity in patients with idiopathic inflammatory myopathies (IIM) are scarce and inconsistent.
W. Che, H. Westerlind, I. Lundberg, K. Hellgren, R. Kuja-Halkola, M. Holmqvist   +5 more
semanticscholar   +1 more source

Failure of daratumumab in the treatment of anti-synthetase syndrome: A case report

SAGE Open Medical Case Reports
Anti-synthetase syndrome is a subset of idiopathic inflammatory myopathies, for which refractory disease can be difficult to treat. Daratumumab, an anti-CD38 monoclonal antibody primarily used in hematologic malignancies, has recently shown promise in ...
Nam Nguyen, Valérie Leclair, Rayan Kaedbey, Marie Hudson   +3 more
doaj   +1 more source

PANNICULITIS IN DERMATOMYOSITIS

Научно-практическая ревматология, 2016
Dermatomyositis (DM) and polymyositis (PM) belong to idiopathic inflammatory myopathies (IIM) and are characterized by inflammatory injury to the skeletal muscles.
O. A. Antelava, O. N. Egorova, B. S. Belov, S. G. Radenska-Lopovok, A. N. Khelkovskaya-Sergeeva, S. I. Glukhova   +5 more
doaj   +1 more source

Alu Overexpression Leads to an Increased Double‐stranded RNA Signature in Dermatomyositis

Arthritis &Rheumatology, Accepted Article.
Objective Dermatomyositis is an autoimmune condition characterized by a high interferon signature of unknown etiology. Because coding sequences constitute <1.2% of our genomes, there is a need to explore the role of the non‐coding genome in disease pathogenesis.
Rayan Najjar, Andrew Mammen, Tomas Mustelin   +2 more
wiley   +1 more source

The impact of the COVID-19 pandemic on patients with juvenile idiopathic inflammatory myopathies

Pediatric Rheumatology Online Journal, 2023
Background Throughout the COVID-19 pandemic, there have been concerns regarding the risks of infection in patients with autoimmune disease. In this study, we investigated the impact of the pandemic on patients with juvenile idiopathic inflammatory ...
Dawn M. Wahezi, Dominique Jerome, Evin Rothschild, Belina Yi, Jeffrey Dvergsten, Stacey Tarvin, Susan Kim, Tamar Rubinstein, for the CARRA JDM workgroup   +8 more
doaj   +1 more source

Evolving Real‐World Data and Evidence Use for New Drugs and Regenerative Medical Products Approvals in Japan—An Analysis of the 6‐Year Trend

Clinical Pharmacology &Therapeutics, EarlyView.
Several regulatory initiatives have been made to clarify the acceptability and requirements of real‐world data and real‐world evidence (RWD/E) for the benefit/risk assessment of new medical products in Japan. The objectives of this review were to characterize the use of RWD/E in regulatory applications of new medical products and to describe the ...
Suguru Okami, Kako Shimotsumagari, Yasunari Sadatsuki   +2 more
wiley   +1 more source

Miopatías inflamatorias

Revista Médica Clínica Las Condes, 2018
RESUMEN: Las miopatías inflamatorias son un grupo heterogéneo de enfermedades adquiridas del músculo estriado esquelético que comparten la injuria muscular inmunomediada como característica común.
Jorge A. Bevilacqua, MD, PhD, Nicholas Earle, MD   +1 more
doaj   +1 more source

Sporadic inclusion body myositis in the rheumatology clinic

Indian Journal of Rheumatology, 2020
Sporadic inclusion body myositis (sIBM) is a progressive and insidious skeletal muscle disorder characterized classically by the quadriceps, wrist, and finger flexor weakness.
Fernando Henrique Carlos de Souza, Gustavo Luiz Behrens Pinto, Jean Marcos de Souza, Pablo Arturo Olivo Pallo, Leonardo Santos Hoff, Samuel Katsuyuki Shinjo   +5 more
doaj   +1 more source

Survival of Patients With Idiopathic Inflammatory Myopathies in Slovenia

Frontiers in Medicine, 2021
Background: Idiopathic inflammatory myopathies (IIMs) are rare systemic diseases associated with significant morbidity and mortality. The aim of our study was to estimate for the first time the survival of IIM patients in Slovenia.Methods: We included ...
Alojzija Hočevar, Alojzija Hočevar, Andrej Viršček, Monika Krošel, Monika Krošel, Suzana Gradišnik, Žiga Rotar, Žiga Rotar, Matija Tomšič, Matija Tomšič, Iztok Holc, Iztok Holc   +11 more
doaj   +1 more source

Reproductive health aspects in men with idiopathic inflammatory myopathy: a multicenter study [PDF]

, 2009
OBJECTIVE: To evaluate reproductive health of males with idiopathic inflammatory myopathies (IIM), and comparing them with a control group. METHODS: Demographic data, urologic evaluation (including pubertal parameters and sexual/erectile function ...
Bonfá, Eloisa Silva Dutra de Oliveira, Borges, Claudia Tereza Lobato, Hallak, Jorge, Hilário, Maria Odete Esteves, Leal, Marta Miranda, Moraes, Ana Julia Pantoja, Ronchezel, Marcos, Saito, Osmar, Sallum, Adriana Maluf Elias, Silva, Clovis Artur Almeida da, Terreri, Maria Teresa Ramos Ascensão   +10 more
core   +2 more sources