Results 141 to 150 of about 11,875 (182)

Idiopathic inflammatory myopathies

Best Practice & Research Clinical Rheumatology, 2012
Inflammatory myopathies are chronic, immune-mediated diseases characterised by progressive proximal muscle weakness. They encompass a variety of syndromes with protean manifestations. The diagnosis is based on Bohan and Peter's classification criteria, which nowadays seem to be obsolete.
Melinda, Vincze, Katalin, Danko
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Idiopathic Inflammatory Myopathies

Rheumatic Disease Clinics of North America, 1990
The idiopathic inflammatory myopathies are a heterogeneous group of uncommon diseases. The incidence rate of IIM is approximately 5 cases per million population, but there appears to be an increase in the rate over the last two decades, particularly in black females.
M E, Cronin, P H, Plotz
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Idiopathic Inflammatory Myopathies

DeckerMed Neurology, 2002
The idiopathic inflammatory myopathies (IIMs), also known as myositis syndromes, are a collection of heterogeneous disorders that share the common feature of chronic muscle inflammation of unknown cause. These disorders may occur in adults or children and are sometimes associated with other connective tissue disorders and a variety of cancers.
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Idiopathic Inflammatory Myopathies

Rheumatic Disease Clinics of North America, 2019
Major advances have been made in the field of idiopathic inflammatory myopathies (IIM), or myositis, that are likely to facilitate development of new therapeutic strategies that have not yet been applied in this group of diseases. These advances include new classification criteria to better identify the patients with IIM, detection of several new ...
Jiří, Vencovský, Helene, Alexanderson, Ingrid E, Lundberg   +2 more
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Treatment of idiopathic inflammatory myopathies

Current Opinion in Neurology, 2003
This article reviews the results of recent therapeutic trials in dermatomyositis, polymyositis, and inclusion body myositis and suggests an approach to treating patients with inflammatory myopathy.We reviewed 10 double-blind, placebo-controlled therapeutic trials in patients with inflammatory myopathy.
Anthony A, Amato, Robert C, Griggs
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Chemokines in idiopathic inflammatory myopathies

Frontiers in Bioscience, 2008
The idiopathic inflammatory myopathies (IIM) represent a heterogeneous group of acquired muscle diseases. The three best-studied subgroups: dermatomyositis (DM), polymyositis (PM), and sporadic inclusion body myositis (IBM), differ considerably both clinically and pathophysiologically.
Boel, De Paepe, Kim K, Creus, Jan L, De Bleecker   +2 more
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Biologics for idiopathic inflammatory myopathies

Current Opinion in Rheumatology, 2017
Purpose of review As treatment of refractory cases of idiopathic inflammatory myopathies (IIMs) has been challenging, there is growing interest in assessing novel biologics that target various pathways implicated in the pathogenesis of IIM.
Siamak, Moghadam-Kia, Rohit, Aggarwal, Chester V, Oddis   +2 more
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Idiopathic Inflammatory Myopathies

Continuum
This article describes the various idiopathic inflammatory myopathies, including their clinical presentation, pathogenesis, diagnosis, and treatments. While many disorders fall under this umbrella, this article focuses on dermatomyositis, antisynthetase syndrome, immune-mediated necrotizing myopathy, polymyositis, and overlap syndrome.The diagnosis of ...
Mohammad Kian, Salajegheh, Anthony A, Amato   +1 more
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Idiopathic inflammatory myopathies—a review

Clinical Rheumatology, 2015
The idiopathic inflammatory myopathies (IIM) constitute a subset of autoimmune conditions primarily affecting muscle, along with many extra-muscular manifestations. Proximal muscle weakness is the dominant symptom in the IIM. In addition, many patients will have cutaneous manifestations, pulmonary manifestations, and arthritis.
Jonathan, Jones, Robert, Wortmann
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Arthritis in Idiopathic Inflammatory Myopathies

Current Rheumatology Reports, 2019
Arthritis is a well-recognized symptom of idiopathic inflammatory myopathies (IIM). We provide a summary of available data regarding the epidemiology, clinical characteristics, and autoantibody associations of joint involvement in various forms of IIM.Arthritis is reported in 18-55% of patients with IIM.
Martin, Klein, Heřman, Mann, Jiří, Vencovský   +2 more
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