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Pathogenesis of idiopathic inflammatory myopathies
Current Rheumatology Reports, 2006The idiopathic inflammatory myopathies, myositis, are characterized by a chronic course with decreased muscle endurance and by infiltrates of T lymphocytes and macrophages in muscle tissue. Treatment with immunosuppressives rarely leads to recovery of muscle function, despite abolishment of inflammatory cell infiltrates in muscle tissue.
Cecilia, Grundtman, Ingrid E, Lundberg
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Registries in idiopathic inflammatory myopathies
Current Opinion in Rheumatology, 2013The idiopathic inflammatory myopathies myositis are rare diseases with limited information on risk factors for disease and prognosis. The aim of this review is to give an overview of how registries can be used in myositis research.Population-based registries have been used in a number of incidence and prevalence studies in the review period and have ...
Ingrid E, Lundberg, John, Svensson
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Genetics of the idiopathic inflammatory myopathies
Current Opinion in Rheumatology, 1996Genetic predisposition to development of the idiopathic inflammatory myopathies is probably multifactorial. Major histocompatibility complex associations with these diseases provide the strongest evidence for a genetic component. In Caucasoids, haplotypes marked by B8/DR3 are associated with each of the clinical subgroups, except mixed connective ...
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Juvenile Idiopathic Inflammatory Myopathies
Pediatric Clinics of North America, 2018The juvenile idiopathic inflammatory myopathies (JIIM) are a group of rare, chronic, autoimmune illnesses that affect muscle and, to a lesser extent, skin. The presence of new-onset weakness and, in juvenile dermatomyositis, typical rahes, should lead to consideration of these diagnoses.
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