Results 91 to 100 of about 12,925 (211)
Wake‐promoting neuromodulators in Alzheimer's disease: Implications for sleep and brain clearance
Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.Abstract Neuromodulatory subcortical systems (NSS) regulate arousal, cognition, and sleep–wake transitions through widespread influence on cortical and subcortical networks. Increasing evidence links dysfunction of these systems to the pathogenesis of Alzheimer's disease (AD). Degeneration and dysregulation of NSS occurs during the preclinical phase of
Taylor J. Pedersen +7 more
wiley +1 more source
Diffusion tensor imaging with direct cytopathological validation: Characterisation of decorin treatment in experimental juvenile communicating hydrocephalus [PDF]
, 2016 BACKGROUND: In an effort to develop novel treatments for communicating hydrocephalus, we have shown previously that the transforming growth factor-β antagonist, decorin, inhibits subarachnoid fibrosis mediated ventriculomegaly; however decorin’s ability ...
Abdullah, Osama +6 more
core +3 more sources
Shunting for idiopathic normal pressure hydrocephalus
Cochrane Database of Systematic ReviewsNormal pressure hydrocephalus (NPH) occurs when the brain ventricles expand, causing a triad of gait, cognitive, and urinary impairment. It can occur after a clear brain injury such as trauma, but can also occur without a clear cause (termed idiopathic, or iNPH). Non-randomised studies have shown a benefit from surgically diverting ventricular fluid to
Ronald, P +6 more
openaire +3 more sources
Idiopathic Normal Pressure Hydrocephalus – What We Know
Maedica - A Journal of Clinical Medicine, 2019 Idiopathic normal pressure hydrocephalus is a neurological disorder with clinical diagnosis and imaging confirmation that benefits from a neurosurgical therapeutic solution in the vast majority of cases. Prevalence among the general population is not well defined at this time, but prevalence and incidence in developed countries is certainly steadily ...
Dumitru, Baltatanu, Mihai, Berteanu
openaire +2 more sources
Fluids and Barriers of the CNSBackground Bidirectional reciprocal motion of cerebrospinal fluid (CSF) was quantified using four-dimensional (4D) flow magnetic resonance imaging (MRI) and intravoxel incoherent motion (IVIM) MRI.
Shigeki Yamada +9 more
doaj +1 more source
Diagnosis of idiopathic normal pressure hydrocephalus is supported by MRI-based scheme: a prospective cohort study [PDF]
, 2010 Background Idiopathic normal pressure hydrocephalus (iNPH) is a treatable neurological syndrome in the elderly. Although the magnetic resonance imaging (MRI) findings of tight high-convexity and medial subarachnoid spaces and the ventriculo-peritoneal ...
Mori Etsuro +3 more
core +2 more sources
Hidden aqueductal stenosis associated to bilateral idiopathic foramina of Monro stenosis mimicking a Chiari I malformation? Case report [PDF]
, 2018 A 39-year old man came to our outpatient clinic with long history of unspecific symptoms and signs. Cerebral MRI showed herniation of the cerebellar tonsils of more than 1cm below the foramen magnum and a triventricular hydrocephalus.
Bartoli, Andrea +3 more
core
Abnormal Gray Matter Structural Networks in Idiopathic Normal Pressure Hydrocephalus
Frontiers in Aging Neuroscience, 2018 Purpose: Idiopathic normal pressure hydrocephalus (iNPH) is known as a treatable form of dementia. Network analysis is emerging as a useful method to study neurological disorder diseases. No study has examined changes of structural brain networks of iNPH
Le-Kang Yin +9 more
doaj +1 more source
Investigating cerebral oedema using poroelasticity [PDF]
, 2015 Cerebral oedema can be classified as the tangible swelling produced by expansion of the interstitial fluid volume. Hydrocephalus can be succinctly described as the abnormal accumulation of cerebrospinal fluid (CSF) within the brain which ultimately leads
Chou, D +6 more
core +1 more source