Beyond the Curve: The Muscle-Specific Asymmetries of Adolescent Idiopathic Scoliosis. [PDF]
Asymmetries in paraspinal muscle volume, intramuscular fat, and fat‐free muscle, observed across 11 vertebral levels, were greater in Adolescents with Idiopathic Scoliois (AIS) than in typically developing controls. Muscle asymmetries follow the shape of the scoliotic curve, typically with greater muscle volumes and intramuscular fat on the concave ...
Duncombe P +5 more
europepmc +2 more sources
PIEZO1-Primary Cilia Axis Mediates Compressive Stress-Induced Growth Plate Degeneration and Ossification in Adolescent Idiopathic Scoliosis. [PDF]
This study investigates Adolescent Idiopathic Scoliosis (AIS), uncovering the core mechanism of mechanical stress‐induced growth plate degeneration and ossification: the mechanosensitive ion channel PIEZO1 colocalizes with primary cilia in chondrocytes, forming a signaling axis.
Chen F +12 more
europepmc +2 more sources
Effect of Surgical Fusion on Volitional Weight-Shifting in Individuals With Adolescent Idiopathic Scoliosis [PDF]
Study Design Prospective. Objectives The goals of this study were to (1) evaluate the differences in weightbearing symmetry between individuals with adolescent idiopathic scoliosis (AIS) and typically developing controls; (2) observe the effect of ...
Graf, Adam +8 more
core +3 more sources
Inheritance and genetics in idiopathic scoliosis [PDF]
Idiopathic scoliosis is the most common spine deformity, affecting approximately 3% of children and adolescents. Its aetiology is still unknown. However, relatives of individuals with idiopathic scoliosis have a higher risk of developing scoliosis ...
Grauers, Anna
core +1 more source
Effect of Lowest Instrumented Vertebra on Trunk Mobility in Patients With Adolescent Idiopathic Scoliosis Undergoing a Posterior Spinal Fusion [PDF]
Study Design Prospective. Objectives The goal of this study was to evaluate the effect of posterior spinal fusion surgery terminating at different lowest instrumented vertebrae (LIV) on trunk mobility in individuals with adolescent idiopathic scoliosis (
Anissipour, Alireza K. +10 more
core +2 more sources
Propionibacterium acnes infections in patients with idiopathic scoliosis: a case-control study and review of the literature. [PDF]
Purpose:Surgical site infection (SSI) caused by Propionibacterium acnes is an infrequent but devastating complication after spinal fusion. The purpose of this study was to identify risk factors for SSI with Propionibacterium acnes after spinal fusion for
Blanco, J +6 more
core +2 more sources
Relationship between thoracic kyphosis and neural axis abnormalities in patients with adolescent idiopathic scoliosis. [PDF]
Purpose:Previous studies have suggested an association between increased thoracic kyphosis and neural axis abnormalities in patients with adolescent idiopathic scoliosis (AIS). However, the basis for this finding is unclear, and this association has been
Blanco, J +5 more
core +2 more sources
Chylous Leak During Posterior Approach to Juvenile Scoliosis Surgery: A Case Report. [PDF]
CaseWe report the first documented case of chylous leak recognized intraoperatively during posterior spinal instrumentation and fusion for juvenile scoliosis in a female patient with a history of thoracotomy and decortication for an empyema ...
Choi, Daniel E +5 more
core +2 more sources
Genetic risk for aortic aneurysm in adolescent idiopathic scoliosis [PDF]
BACKGROUND: Scoliosis is a feature of several genetic disorders that are also associated with aortic aneurysm, including Marfan syndrome, Loeys-Dietz syndrome, and type-IV Ehlers-Danlos syndrome.
Alvarado, David M +9 more
core +2 more sources
Common polymorphisms in human lysyl oxidase genes are not associated with the adolescent idiopathic scoliosis phenotype [PDF]
BACKGROUND: Although adolescent idiopathic scoliosis affects approximately 3% of adolescents, the genetic contributions have proven difficult to identify.
Dobbs, Matthew B +7 more
core +3 more sources

