Results 61 to 70 of about 34,982 (211)

Acetylation Regulates ACSL4 Degradation Through Chaperone‐Mediated Autophagy to Alleviate Intervertebral Disc Degeneration

open access: yesAdvanced Science, Volume 13, Issue 8, 9 February 2026.
Intervertebral disc degeneration is triggered by ACSL4 accumulation‐mediated ferroptosis of nucleus pulposus cells due to CMA dysfunction. KAT2B promotes ACSL4 degradation via CMA through acetylation. AAV‐mediated LAMP2A delivery or engineered exosomes rescue nucleus pulposus cell senescence and disc degeneration.
Zhouwei Wu   +10 more
wiley   +1 more source

Measures of Health-Related Quality of Life Outcomes in Pediatric Neurosurgery: Literature Review [PDF]

open access: yes, 2019
Background Improving value in healthcare means optimizing outcomes and minimizing costs. The emerging pay-for-performance era requires understanding of the effect of healthcare services on health-related quality of life (HRQoL).
Desai, Virendra R.   +4 more
core   +1 more source

Impact of Growth Hormone Treatment in Children From an Extended Family With ACAN ‐Related Short Stature

open access: yesClinical Genetics, Volume 109, Issue 2, Page 374-379, February 2026.
This study evaluated growth hormone (GH) therapy in children from an extended family with genetically confirmed ACAN‐related short stature. While GH treatment improved growth velocity, the response varied among individuals, and its long‐term impact on final adult height remains to be determined.
Einat Shalev‐Goldman   +5 more
wiley   +1 more source

Schroth Method Exercises for Treating Idiopathic Adolescent Scoliosis; A Narrative Review

open access: yesمجله پژوهش در علوم توانبخشی, 2019
- Introduction: Scoliosis is a 3-dimensional spinal deformity. In recent years, more attention has been paid to scoliosis specific exercises. Among different exercise methods for treating scoliosis, the Schroth’s method is the most recognized and widely ...
Javid Mostamand, Farnaz Jokar
doaj   +1 more source

3D reconstruction of ribcage geometry from biplanar radiographs using a statistical parametric model approach [PDF]

open access: yes, 2014
Rib cage 3D reconstruction is an important prerequisite for thoracic spine modelling, particularly for studies of the deformed thorax in adolescent idiopathic scoliosis.
AUBERT, Benjamin   +4 more
core   +2 more sources

How Does Pulmonary Function Change in Patients With Severe Thoracic Scoliosis 2 Years After One‐Stage Low‐Grade Osteotomy and Posterior Corrective Surgery?

open access: yesOrthopaedic Surgery, Volume 18, Issue 2, Page 251-260, February 2026.
One‐stage low‐grade osteotomy surgery with apical region correction and global balance significantly improved pulmonary function in severe thoracic scoliosis patients at 2‐year follow‐up. Increased thoracic height is regarded as the key correlating factor.
Junduo Zhao   +6 more
wiley   +1 more source

Magnitude of thoracic spine deformity affecting morphologial characteristics of paraspinal muscles in patients with severe idiopathic scoliosis

open access: yesГений oртопедии, 2021
Introduction Morphological, biochemical and histopathological characteristics of paraspinal muscles have been well described in patients with idiopathic scoliosis.
Elena N. Shchurova   +2 more
doaj   +1 more source

Idiopathic scoliosis and associated factors among school children: a school-based screening in Ethiopia

open access: yesArchives of Public Health, 2021
Background Early detection of scoliosis is a preface to prevent progression. In resource-constrained countries like Ethiopia, there is a need for a cost-effective reliable solution for screening.
Moges Gashaw   +2 more
doaj   +1 more source

The pendulum swings back to scoliosis screening: screening policies for early detection and treatment of idiopathic scoliosis - current concepts and recommendations [PDF]

open access: yes, 2013
This editorial article initiates the school scoliosis screening thematic series of the Scoliosis journal. The various issues on screening policies are discussed; clinical and practical recommendations of setting up school screening programs are also ...
Grivas, Theodoros B   +5 more
core   +1 more source

Selection of the Lowest Instrumented Vertebra in Lenke‐5 AIS: A Case Study With at Least 5‐Year Follow‐Up

open access: yesOrthopaedic Surgery, Volume 18, Issue 2, Page 289-299, February 2026.
While distal fusion to LTV‐1 on upright radiographs yields satisfactory outcomes in a certain proportion of AIS patients, we hypothesized that the relaxed spinal posture in supine position could facilitate a more conservative fusion strategy. This study therefore investigated the utility of supine imaging for LIV selection in Lenke‐5 AIS.
Zhen Wang   +5 more
wiley   +1 more source

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