Results 241 to 250 of about 50,576 (287)

The effect of treatment with recombinant human growth hormone (rhGH) on linear growth and adult height in children with idiopathic short stature (ISS): a systematic review and meta-analysis

Journal of Pediatric Endocrinology & Metabolism (JPEM), 2020
Objectives Idiopathic short stature (ISS) is a recognized, albeit a controversial indication for treatment with recombinant human growth hormone (rhGH).
G. Paltoglou, I. Dimitropoulos, G. Kourlaba, E. Charmandari   +3 more
semanticscholar   +1 more source

Genetic studies in idiopathic short stature

Current Opinion in Pediatrics, 2000
Idiopathic short stature (ISS) refers to a heterogeneous group of children with marked growth failure of unknown cause, and encompasses familial short stature and constitutional delay of growth. It has been postulated that specific genetic mutations may explain certain cases of growth failure.
openaire   +3 more sources

Spontaneous Adult Height in Idiopathic Short Stature

Hormone Research, 1995
Two hundred and thirty-six patients with idiopathic short stature (ISS) (184 m, 52 f) who presented at a mean age of 12.2 (range 2.8-17.5) years, a mean height of -2.16 standard deviation score (SDS), a mean target height (THT) of -0.27 SDS (m = f), were reinvestigated at a mean age of 20.5 (range 18-24) years. 182(142 m, 37 f) (67%) had reached normal
K Kistner, Hartmut A. Wollmann, Michael B. Ranke, Werner F. Blum, M L Grauer   +4 more
openaire   +3 more sources

Psychological Functioning in Idiopathic Short Stature

Hormone Research in Paediatrics, 2011
Living with idiopathic short stature (ISS) may entail significant risks to psychological functioning and quality of life. Apparent inconsistency among study findings can be resolved if methodological differences among study designs are taken into account (i.e., definition of particular endpoints, sample selection from clinic or population, source of ...
openaire   +2 more sources

Impact of growth hormone treatment on scoliosis development and progression: analysis of 1128 patients with idiopathic short stature

Journal of Pediatric Endocrinology & Metabolism (JPEM), 2020
Objectives The purpose of this study was to evaluate the impact of recombinant human growth hormone (rhGH) on the development and progression of scoliosis in patients with idiopathic short stature (ISS).
Sejung Park, Keun-Ho Lee, C. Lee, Ki-Tack Kim, Jun-Hyuk Jang, D. Shin, Min Sun Kim, Jiyeon Kim, S. Cho, D. Jin   +9 more
semanticscholar   +1 more source

Idiopathic Short Stature: Diagnostic and Therapeutic Approach [PDF]

, 2013
Our clinical case for discussion is about a short statured boy who was 14.6 years old at his first evaluation. He was born after a 39-week gestation as the third child of a non-consanguineous marriage. His birth weight was 3.250 g (−0.3 SDS), and his birth length was not available. His neuropsychomotor development was normal, his school performance was
Alexander A. L. Jorge, Ana Pinheiro Machado Canton   +1 more
openaire   +1 more source

Idiopathic short stature: Definition, epidemiology, and diagnostic evaluation

Growth Hormone & IGF Research, 2008
Idiopathic short stature is a condition in which the height of the individual is more than 2 SD below the corresponding mean height for a given age, sex and population, in whom no identifiable disorder is present. It can be subcategorized into familial and non-familial ISS, and according to pubertal delay.
Wit, J. M., Clayton, P. E., Rogol, A. D., Savage, M. O., Saenger, P. H., Cohen, P.   +5 more
openaire   +3 more sources

Comparison of nocturnal and morning ghrelin concentration in children with growth hormone deficiency and with idiopathic short stature

Chronobiology International, 2020
Ghrelin – a growth hormone (GH) secretagogue – presents a circadian rhythm with higher nocturnal than diurnal concentration (similar to GH). However, daily ghrelin production depends on food intake and nutritional state; it is increased in the fasting ...
Renata Stawerska, Marzena Kolasa-Kicińska, Anna Łupińska, M. Hilczer, A. Lewiński   +4 more
semanticscholar   +1 more source

Normal Variant and Idiopathic Short Stature

2018
This chapter reviews normal variant short stature, comprised of both familial short stature (FSS) and constitutional delay of growth and puberty (CDGP), as well as idiopathic short stature (ISS). FSS and CDGP are physiologic variants of short stature without an organic cause. Although ISS is not a “normal variant” of short stature, as with FSS and CDGP
Mary M. Lee, Penny M. Feldman
openaire   +2 more sources

Idiopathic short stature: Management and growth hormone treatment

Growth Hormone & IGF Research, 2008
In the management of ISS auxological, biochemical, psychosocial and ethical elements have to be considered. In boys with constitutional delay of growth and puberty androgens are effective in increasing height and sexual characteristics, but adult height is unchanged.
Alan D. Rogol, Jan M. Wit, Pinchas Cohen, Judith L. Ross, Judith L. Ross, Martin O. Savage, Edward O. Reiter, Paul Saenger   +7 more
openaire   +3 more sources