Results 61 to 70 of about 12,816 (223)

How I treat thrombotic thrombocytopenic purpura and atypical haemolytic uraemic syndrome

open access: yes, 2014
Thrombotic thrombocytopenic purpura (TTP) and atypical haemolytic uraemic syndrome (aHUS) are acute, rare life-threatening thrombotic microangiopathies that require rapid diagnosis and treatment.
Goodship, T, Scully, M
core  

Pathogenetic justification for the therapy of idiopathic thrombocytopenic purpura (primary immune thrombocytopenia) in adults

open access: yes, 2018
The review presents current data on key mechanisms of the pathogenesis of idiopathic thrombocytopenic purpura and comparative characteristics of main therapy methods.
I I Zotova, S V Gritsaev
core   +1 more source

Acute Idiopathic Thrombocytopenic Purpura: A Case Report

open access: yes, 2004
This paper presents a case report of a patient who showed severe oral and skin manifestations of acute idiopathic thrombocytopenic purpura, followed by a discussion of the approach to its differential diagnosis and management in the context of the ...
A. John Duxbury   +2 more
core   +1 more source

Chemotherapy in a Patient with Prior History of Idiopathic Thrombocytopenic Purpura

open access: yesActa Medica, 2003
We described a 67 years old small-cell lung cancer patient with a prior history of idiopathic thrombocytopenic purpura (ITP) who was treated with successful chemotherapy.
Kouji Kanemoto   +2 more
doaj   +1 more source

A Difficult‐to‐Manage Case of Primary Idiopathic Erythromelalgia—Case Report

open access: yesClinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Erythromelalgia is a rare condition with symptoms of erythema, warmth, and painful extremities exacerbated by warmth and relieved by cooling. Pain management is often challenging. The sodium channel blocker, lacosamide, was most effective in this patient.
Sarah Wide   +3 more
wiley   +1 more source

Successful Treatment of Aplastic Anemia With Eltrombopag During Pregnancy: A Short Report

open access: yeseJHaem, Volume 7, Issue 2, April 2026.
ABSTRACT Introduction Aplastic anemia (AA) is a rare bone marrow failure syndrome with pancytopenia, mainly due to immune‐mediated stem cell destruction. First‐line therapy for acquired severe AA ≥ 50 years/non‐severe AA (NSAA) requiring treatment is immunosuppressive therapy with horse anti‐thymocyte globulin, cyclosporine A (CSA), and eltrombopag ...
Sandra M. Frey   +3 more
wiley   +1 more source

The relationship between ADAMTS13 genotype and phenotype in congenital thrombotic thrombocytopenic purpura and characterisation of ADAMTS13 mutants

open access: yes, 2015
Congenital thrombotic thrombocytopenic purpura (TTP) is a thrombotic microangiopathy, usually involving ADAMTS13 gene defects. ADAMTS13 processes the multimeric plasma glycoprotein Von Willebrand factor making it less reactive to platelets.
Underwood, MI
core  

Idiopathic thrombocytopenic purpura and MMR vaccine

open access: yes, 2001
A causal association between measles mumps–rubella (MMR) vaccine and idiopathic thrombocytopenic purpura (ITP) was confirmed using immunisation/hospital admission record linkage.
Stowe, J.   +5 more
core   +1 more source

Epidemiology and Genetics of Rheumatic Diseases Suggest a Constant Rate of DNA Damage as Underlying Cause

open access: yesImmunology, Volume 177, Issue 4, Page 736-748, April 2026.
A constant rate of DNA damage that is not perfectly repaired will cause a constant rate of DNA mutations. The chance of mutation will increase if DNA is prone to damage, such as occurs in somatic hypermutation (SHM) hotspots and GC‐rich DNA. Thus, if one mutation‐prone DNA site drives disease, the age of onset of disease and degree of penetrance should
Piet C. de Groen
wiley   +1 more source

Adult Idiopathic Thrombocytopenic Purpura

open access: yesHematology, 2003
Idiopathic thrombocytopenic purpura (ITP) in adults is an autoimmune disorder characterised by persistent thrombocytopenia due to autoantibodies directed against platelet antigens. There have been major advances in our understanding of the pathophysiology of ITP and an increasing number of diagnostic tests and treatments available.
Mead, A, Newland, A, Provan, D
openaire   +3 more sources

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