Results 61 to 70 of about 46,023 (268)

Eltrombopag: an update on the novel, non-peptide thrombopoietin receptor agonist for the treatment of immune thrombocytopenia [PDF]

open access: yes, 2018
Immune thrombocytopenia (ITP) is characterised by a transient or persistent decrease in platelets accompanied by an increased risk of bleeding, which can have a significant negative impact on patients' health-related quality of life.
Imbach, Paul, Kühne, Thomas
core  

Aplastic Crisis as Primary Manifestation of Systemic Lupus Erythematosus [PDF]

open access: yes, 2011
Aplastic crisis is an unusual feature of systemic lupus erythematosus (SLE). We report the case of a 54-year-old woman presenting with both (extravascular) Coombs-positive hemolytic anemia and laboratory findings of bone marrow hyporegeneration with ...
Alger M   +23 more
core   +1 more source

Noonan Syndrome Spectrum Disorders Predispose to Systemic Lupus Erythematosus: Case Report and Critical Review of the Literature

open access: yesAmerican Journal of Medical Genetics Part A, Volume 200, Issue 5, Page 1091-1097, May 2026.
ABSTRACT RASopathies are clinically overlapping neurodevelopmental syndromes resulting from germline mutations in genes involved in the rat sarcoma/mitogen‐activated protein kinases (RAS/MAPK) pathway. Historically, RASopathies have been described by clinical phenotypes, such as Noonan syndrome and Neurofibromatosis type I.
Anastasia‐Vasiliki Madenidou   +6 more
wiley   +1 more source

IDIOPATHIC THROMBOCYTOPENIC PURPURA (i.T.P.) [PDF]

open access: yesActa Medica Iranica, 1987
The course of t he disorder is acute and chronic.The acute form o f the disease occurs most c ommonly in children , but is seen i n adults as well . The chronic recurrent f orm occurs most o f t e n in women between t wenty and forty years of age.
Sh. MOHAMEDI M ZAMANIANPOUR ML GHASEMI
doaj   +1 more source

A case of refractory thrombotic thrombocytopenic purpura treated with plasmapheresis and rituximab [PDF]

open access: yes, 2016
Thrombotic thrombocytopenic purpura (TTP) is a rare, life-threatening disorder with no prevalence or incidence studies in sub-Saharan Africa. Acquired TTP has several causes, all of which lead to decreased activity of von Willebrand factor cleaving ...
Kirui, Nicholas, Sokwala, Ahmed
core   +4 more sources

A Difficult‐to‐Manage Case of Primary Idiopathic Erythromelalgia—Case Report

open access: yesClinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Erythromelalgia is a rare condition with symptoms of erythema, warmth, and painful extremities exacerbated by warmth and relieved by cooling. Pain management is often challenging. The sodium channel blocker, lacosamide, was most effective in this patient.
Sarah Wide   +3 more
wiley   +1 more source

Tuberculosis presenting as immune thrombocytopenic purpura [PDF]

open access: yes, 2004
Background Although various hematologic abnormalities are seen in tuberculosis, immune thrombocytopenic purpura is a rare event. Case Presentation We report a case of a 29 year-old male who was presented with immune thrombocytopenia-induced hemoptysis ...
Bahadir-Erdogan Beril   +7 more
core   +2 more sources

Successful Treatment of Aplastic Anemia With Eltrombopag During Pregnancy: A Short Report

open access: yeseJHaem, Volume 7, Issue 2, April 2026.
ABSTRACT Introduction Aplastic anemia (AA) is a rare bone marrow failure syndrome with pancytopenia, mainly due to immune‐mediated stem cell destruction. First‐line therapy for acquired severe AA ≥ 50 years/non‐severe AA (NSAA) requiring treatment is immunosuppressive therapy with horse anti‐thymocyte globulin, cyclosporine A (CSA), and eltrombopag ...
Sandra M. Frey   +3 more
wiley   +1 more source

Occurrence of immune thrombocytopenic purpura in a patient with essential thrombocythemia: How the immune system can overcome a neoplastic clone

open access: yesClinical Case Reports, 2020
Our case highlights the possible coexistence of essential thrombocythemia (ET) and idiopathic thrombocytopenic purpura (ITP), two pathological entities with opposite clinical and laboratory manifestations.
Antonio Carruale   +5 more
doaj   +1 more source

Púrpura trombopénica inmune : múltiples tratamientos para una enfermedad [PDF]

open access: yes, 2012
En el present treball es descriuen les principals característiques clíniques de la purpura trombopènica immune, com ara, la distribució per sexes, edat, la presència d'hemorràgies en el moment del diagnòstic i la seva gravetat, la xifra de plaquetes i la
Lluch García, Rafael   +3 more
core  

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