Results 141 to 150 of about 101,741 (257)

Faunistic inventory of the genus Culicoides (Diptera: Ceratopogonidae) in Mauritius Island, Indian Ocean: Diversity and spatial distribution of species of veterinary interest Inventaire faunistique du genre Culicoides (Diptera: Ceratopogonidae) sur l'île Maurice dans l'océan Indien: diversité et répartition spatiale des espèces présentant un intérêt vétérinaire

open access: yesMedical and Veterinary Entomology, Volume 40, Issue 2, Page 282-293, June 2026.
Four Afrotropical Culicoides species are recorded in Mauritius with suspected or historically involvement in BTV and EHDV transmission. All species were distributed all over the island. While intra‐specific morphological variations were detected, genetic analyses did not reveal any cryptic diversity. Abstract Viruses transmitted by biting midge species
Diana P. Iyaloo   +15 more
wiley   +1 more source

A Topology Optimization Framework for the Inverse Design of Nonlinear Mechanical Metamaterials

open access: yesAdvanced Engineering Materials, Volume 28, Issue 9, 6 May 2026.
This work uses topology optimization to design unit cells for mechanical metamaterials with a prescribed nonlinear stress–strain response. The framework adds contact and postbuckling modeling to synthesize microstructures for three highly nonlinear responses, including pseudoductile behavior, monostable with snap‐through buckling, and bistable ...
Charlie Aveline   +2 more
wiley   +1 more source

Time‐Resolved SAXS Reveals Distinct Millisecond Metal‐Induced Conformational Dynamics of Monomeric α‐Synuclein

open access: yesAdvanced Science, Volume 13, Issue 25, 4 May 2026.
Time‐resolved SAXS reveals how physiologically relevant metal ions shape the earliest conformational responses of monomeric α‐synuclein. Fe3+ induces rapid compaction, Cu2+ generates heterogeneous and partially folded ensembles, while Mn2+ and Zn2+ cause only modest changes.
Rebecca Sternke‐Hoffmann   +3 more
wiley   +1 more source

Different Immune Cells Modified With Chimeric Antigen Receptors Are Being Applied to Ovarian Cancer: Which Is the Most Effective?

open access: yesCancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Ovarian Cancer (OC), the deadliest gynecological malignancy, poses a major therapeutic challenge in advanced stages owing to its high recurrence rate and metastatic potential. In this regard, it is noteworthy that immunotherapy has recently gained significant attention in OC treatment, a phenomenon attributable to notable advances in over‐the ...
Liying Wang   +4 more
wiley   +1 more source

Phase Separation of Parkinson's Disease Protein α‐Synuclein: Mechanistic Insights but Biological Uncertainties

open access: yesChemistryEurope, Volume 4, Issue 5, May 2026.
Parkinson's disease‐associated protein α‐synuclein can assemble into liquid condensates under strongly perturbed in vitro and in vivo experimental conditions, including high protein concentration, macromolecular crowding, and when attached to various tags with cross‐linking ability.
Simran Arora   +1 more
wiley   +1 more source

Gut–Brain Connection: Deciphering Causal Pathways Between Gut Microbiota and Neuroimaging Profiles Through Mendelian Randomization

open access: yesFood Science &Nutrition, Volume 14, Issue 5, May 2026.
This graphical abstract illustrates the bidirectional causal relationships between gut microbiota and brain network connectivity identified using Mendelian randomization analysis. Genome‐wide association study data from the MiBioGen consortium (gut microbiota) and the UK Biobank (brain imaging‐derived phenotypes across seven resting‐state networks ...
Yule Zeng   +5 more
wiley   +1 more source

The Ubiquitin Ligase Zinc Finger SWIM Domain‐Containing Protein 8 Regulates Oligodendrocyte Development Through the Argonaute2/MicroRNA‐7 Axis

open access: yesGlia, Volume 74, Issue 5, May 2026.
ZSWIM8, an E3 ubiquitin ligase that broadly targets IDR‐rich proteins, drives MiR‐7‐dependent AGO2 degradation and the turnover of many RBPs. Loss of ZSWIM8 leads to MiR‐7 accumulation in oligodendrocyte progenitor cells and myelination defects in the developing brain. ABSTRACT Proteostasis of proteins with intrinsically disordered regions (IDRs) is of
Jing Lei   +13 more
wiley   +1 more source

Universal Female Genital Mutilation and High Burden of Infibulation in Mogadishu: Cross‐Sectional Study on Severity, Types, and Associated Factors Among Adolescent Girls in Somalia

open access: yesHealth Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aims The study aimed to investigate the prevalence, determinants, types, severity, and perceived health consequences of Female Genital Mutilation (FGM) among adolescent girls aged 12–19 in Mogadishu, Somalia. The primary objective was to quantify the burden of different FGM types and identify socio‐cultural predictors. Methods A
Ahmed Abdinasir Abdule   +7 more
wiley   +1 more source

An ALS‐associated mutation in the C‐terminal α‐helix of TDP‐43 uncouples condensate formation and amyloid assembly

open access: yesProtein Science, Volume 35, Issue 5, May 2026.
Abstract TAR DNA‐binding protein 43 (TDP‐43) plays a critical role in RNA metabolism and is incorporated into biomolecular condensates called stress granules. In amyotrophic lateral sclerosis (ALS) and several other neurodegenerative disorders, TDP‐43 undergoes aberrant phase transitions, forming insoluble amyloid aggregates, including fibrils composed
Emily J. Byrd   +4 more
wiley   +1 more source

Transmembrane Condensation in Albumin‐Loaded Giant Vesicles Induced by an Intrinsically Disordered Protein

open access: yesChemSystemsChem, Volume 8, Issue 3, May 2026.
An intrinsically disordered protein, Q20, forms transmembrane condensates with albumin‐loaded lipid and hybrid giant vesicles. Condensate insertion and membrane remodeling depend on giant vesicle size and membrane properties, inducing local lipid coupling without leakage and revealing a robust membrane‐condensate interplay.
Paula De Dios Andres   +5 more
wiley   +1 more source

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