Results 21 to 30 of about 3,348 (112)
MolDBG is a site‐aware, sequence‐only framework that unifies drug‐target affinity prediction, binding‐site identification, and affinity‐conditioned molecular generation for structured proteins. Guided by multi‐task binding‐site supervision, it aligns interaction‐critical residues before learning drug‐target representations and simultaneously infers ...
Gang Luo +6 more
wiley +1 more source
Esta pesquisa situa-se no tema de resiliência governamental fiscal e visa apresentar propostas para que o ente se torne mais resiliente frente a crises econômicas.
Anderson Borges Roepke +2 more
doaj
An NbS3/WSe2 van der Waals heterostructure realizes a continuously gate‐tunable self‐powered photovoltaic response through interfacial band‐alignment modulation and reversible built‐in electric‐field switching. The short‐circuit photocurrent scales linearly with incident power density, while short‐circuit photoresponsivity varies linearly with gate ...
Jidong Liu +9 more
wiley +1 more source
A Comparative Study of Vertical Mixing Schemes in Modeling the Bay of Bengal Dynamics
The choice of vertical mixing scheme in ocean models plays an important role in modeling the surface and subsurface circulation and the vertical structure.
Siddhesh Tirodkar +3 more
doaj +1 more source
Diverging Liquid–Liquid Phase Separation Behavior of Different Recombinant Major Ampullate Spidroins
Fibers spun from the MaSp1‐derivative as well as MaSp1‐MaSp2‐mixtures provide a deeper insight into the assembly process of the spidroins and how hierarchical architectures of spider silk fibers could be achieved. ABSTRACT Spider silk fibers show exceptional mechanical properties, based on their underlying spider silk proteins (spidroins) as well as a ...
Tim Schiller +2 more
wiley +1 more source
A partir de registros de genealogia e controle leiteiro e reprodutivo fornecidos pela Associação Brasileira dos Criadores de Girolando, foram estimados os efeitos de diferença genética aditiva entres as raças Holandesa e Gir, de dominância e de ...
Olivardo Facó +5 more
doaj +1 more source
By applying self-made intensive dual-phase steel alloy (IDP) powders for repairing various substrate materials, laser additive manufacturing (LAM) test was conducted on the surface of 2205 dual-phase stainless steels to evaluate performance of the laser ...
Jia-Hao Wen +6 more
doaj +1 more source
Fracture of the mandible treatment in a child: a simplified technique
After being hit by a motorcycle a seven-year old boy presented with a displaced fracture of the body of the right mandible [type III]. In the absence of orthodontic internal fixation or ligature wire equipment suture material was used to provide ...
Christoph H. Houben +2 more
doaj +1 more source
α‐Synuclein Forms Distinct Micelle‐Like Assemblies at Low Ionic Strengths
At high ionic strength, α‐synuclein forms diverse assemblies, including oligomers, fibrils, and condensates. Here, we show that at low ionic strength, α‐synuclein adopts a distinct, low‐abundance assembly state. These assemblies maintain a constant size above a critical concentration and do not coalesce, suggesting a micelle‐like organization ...
Sophie Hertel +10 more
wiley +1 more source

