Results 81 to 90 of about 3,332 (169)

Water, Hygiene and Inequality: Keys to Understanding and Combating the Current Cholera Epidemic in the Democratic Republic of Congo—A Narrative Review

Health Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background and Aim The Democratic Republic of the Congo (DRC) is among the countries most affected by cholera in the world. Since the 1970s, endemic foci have persisted in the eastern lake provinces, where chronic armed conflict, massive population displacement, and extreme socioeconomic inequalities create particularly favorable conditions ...
Hermann Yokolo, Ahmed Tayebelasma, Gaaitri Lohano, Basma Khawar Khan, Ayesha Junaid   +4 more
wiley   +1 more source

The Effect of Protein Tagging on Aggregation and Phase Separation

Journal of Cellular Biochemistry, Volume 127, Issue 6, June 2026.
ABSTRACT Protein tags are widely used for purification, solubilization, detection, and imaging, yet they can substantially alter protein self‐assembly. This interference is particularly significant for intrinsically disordered proteins and low‐complexity domains, whose aggregation and phase separation are mediated by weak multivalent interactions that ...
Harunobu Saito, Kenji Sugase
wiley   +1 more source

O Pensamento de Peter Häberle na Jurisprudência do Supremo Tribunal Federal

Direito Público, 2010
   
ANDRÉ RUFINO DO VALE, GILMAR FERREIRA MENDES   +1 more
doaj  

Detrimental Effect of Low‐Magnitude High‐Frequency Vibration in an Ex Vivo Model of Intervertebral Disc Degeneration Despite Estrogen Treatment

JOR SPINE, Volume 9, Issue 2, June 2026.
Low‐magnitude high‐frequency vibration (LMHFV), with or without 17β‐oestradiol (E2), exacerbated papain‐induced bovine intervertebral disc degeneration, reducing cell viability, impairing matrix production, and increasing inflammation. E2 showed no protective effect against papain‐induced degeneration or LMHFV.
Jan Ulrich Jansen, Felizitas Figel, Franziska Widmayer, Morten Vogt, Maria Ahrens, Hans‐Joachim Wilke, Anita Ignatius, Melanie Haffner‐Luntzer, Cornelia Neidlinger‐Wilke, Graciosa Quelhas Teixeira   +9 more
wiley   +1 more source

Deep learning imaging phenotype can classify metabolic syndrome and is predictive of cardiometabolic disorders

Journal of Translational Medicine
Background Cardiometabolic disorders pose significant health risks globally. Metabolic syndrome, characterized by a cluster of potentially reversible metabolic abnormalities, is a known risk factor for these disorders.
Jacob S. Leiby, Matthew E. Lee, Manu Shivakumar, Eun Kyung Choe, Dokyoon Kim   +4 more
doaj   +1 more source

Exploring and Targeting the Connection of Iron and Copper Homeostasis to Neurodegenerative Diseases

MedComm, Volume 7, Issue 6, June 2026.
Iron and copper dyshomeostasis, along with their interactions with key intrinsically disordered proteins (e.g., Aβ, tau, α‐synuclein) have a strong implication in the onset and progression of neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), Prion diseases (PrDs), Huntington's disease (HD), Wilson's disease (WD),
Xin Liu, Lin Jia, Kerong Wu, Mo Chen, Jichao Sun, Chuanbin Yang, Chengchao Xu, Jie Sun, Jigang Wang, Lingyun Dai   +9 more
wiley   +1 more source

CISP, an Intrinsically Disordered Cold‐Inducible Barley Protein, Functions as a Small RNA Chaperone

Plant Direct, Volume 10, Issue 6, June 2026.
ABSTRACT Low temperatures are a major environmental stress that limits plant growth and development. Understanding the molecular mechanism of cold tolerance is therefore essential for improving crop performance through molecular breeding. In this study, we focused on CISP, a small, previously uncharacterized protein, specifically induced in barley ...
Yutaro Okumura, Md. Maksudul Haque, Shin‐ichiro Kidou   +2 more
wiley   +1 more source

Multidimensional Poverty and Deprivation in Informal Settlements: A Gendered Perspective From the South African Multidimensional Poverty Index

Poverty &Public Policy, Volume 18, Issue 2, June 2026.
ABSTRACT Rapid urbanisation and persistent socio‐economic inequality continue to entrench multidimensional poverty within South Africa's urban informal settlements, with women and female‐headed households experiencing disproportionate deprivation. This study analysed primary household survey data collected in 2023 from 322 households across three ...
Adrino Mazenda, Stellah Lubinga, Hayley Boks, Moses Lubinga   +3 more
wiley   +1 more source

SEGURANÇA E PREVENÇÃO NO VAZAMENTO DE DADOS NO CDC E NA LGPD

Revista de Ciências Jurídicas e Sociais da UNIPAR
O trabalho analisa as mudanças e adaptações na rotina das pessoas introduzidas pelos meios digitais e outros fatores no mundo globalizado. Após a inserção dos dados pessoais para utilização desses meios virtuais, as pessoas, de certa maneira, perdem o ...
Ricardo Morishita, Nyvea Lourenço
doaj   +1 more source

Lipid composition controls the huntingtin exon 1 membrane‐association and differentially modulates its flanking regions' dynamics

Protein Science, Volume 35, Issue 6, June 2026.
Abstract The pathological expansion of the polyglutamine (polyQ) repeat within the first exon of huntingtin (Httex1) protein is a defining hallmark of Huntington's disease (HD). Multiple evidence supports that the membrane recruitment of Httex1 is critical for its self‐assembly and related toxicity in HD.
Tânia Sousa, Gonçalo Damas, Ana Coutinho, Nuno Bernardes, Ana Azevedo, Manuel Prieto, Ana M. Melo   +6 more
wiley   +1 more source