Results 111 to 120 of about 2,703,511 (280)
The role of Id genes on pulmonary hypertension development in left heart failure
American Heart Journal Plus: Cardiology Research and PracticeTo investigate the role of Id genes in the development of pulmonary hypertension (PH) in heart failure (HF) and evaluate genetic variants of the ID genes associated with HF-PH.Experimental study using an AKR/J mouse model of HF-PH and a genetic association study using the UK Biobank cohort.Laboratory animal study and population-based cohort study.AKR/J
Lteif, Christelle +3 more
openaire +2 more sources
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Video Tip: Convert Gene IDs with Biomart
, 2012 I get asked frequently how to convert from one gene identifier to another. This can be tricky, especially when relying on gene symbols, as Will pointed out in a previous post a few years ago. There are several tools that can do this, including DAVID and the previously mentioned new Biomart ID Converter, but I still prefer using the Ensembl Biomart for ...
openaire +1 more source
List of TaqMan Gene Assay IDs.
, 2013 List of TaqMan Gene Assay IDs.
Dominic Henn (289333) +7 more
core +1 more source
FEBS Open Bio, EarlyView.The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti +5 more
wiley +1 more source
IDS Bulletin Terms of Reference
The IDS Bulletin is a digital, fully Open Access, peer-reviewed journal published by the Institute of Development Studies, in continuous regular publication since 1968.
Institute of Development Studies (IDS) (19282513)
core +1 more source
Biological analysis of cancer specific microRNAs on function modeling in osteosarcoma
Scientific Reports, 2017 Osteosarcoma (OS) is the most common bone tumor characterized with a high risk of amputation and malignant morbidity among teenagers and adolescents. However, relevant pathogenic/biological mechanisms underlying OS-genesis remains to be ambiguous.
Hao Wang +8 more
doaj +1 more source
FEBS Open Bio, EarlyView.Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta +7 more
wiley +1 more source
EMBO Molecular Medicine, 2013 Mucopolysaccharidoses type IIIA (MPS‐IIIA) is a neurodegenerative lysosomal storage disorder (LSD) caused by inherited defects of the sulphamidase gene. Here, we used a systemic gene transfer approach to demonstrate the therapeutic efficacy of a chimeric
Nicolina Cristina Sorrentino +10 more
doaj +1 more source