Comparative analysis of plant immune receptor architectures uncovers host proteins likely targeted by pathogens. [PDF]
, 2016 BACKGROUND: Plants deploy immune receptors to detect pathogen-derived molecules and initiate defense responses. Intracellular plant immune receptors called nucleotide-binding leucine-rich repeat (NLR) proteins contain a central nucleotide-binding (NB ...
Cevik, Volkan +4 more
core +11 more sources
HGPGD: the human gene population genetic difference database. [PDF]
PLoS ONE, 2013 Demographic events such as migration, and evolutionary events like mutation and recombination, have contributed to the genetic variations that are found in the human genome.
Yongshuai Jiang +12 more
doaj +1 more source
Frontiers in Neuroscience, 2022 Spinal cord injury-induced immune deficiency syndrome (SCI-IDS) is a disorder characterized by systemic immunosuppression secondary to SCI that dramatically increases the likelihood of infection and is difficult to treat.
Chaochen Li +16 more
doaj +1 more source
HTRIdb: an open-access database for experimentally verified human transcriptional regulation interactions [PDF]
, 2012 Background: The modeling of interactions among transcription factors (TFs) and their respective target genes (TGs) into transcriptional regulatory networks is important for the complete understanding of regulation of biological processes.
Luiz A. Bovolenta +2 more
core +4 more sources
Wheat Disease Resistance Genes and Their Diversification Through Integrated Domain Fusions
Frontiers in Genetics, 2020 Plants are in a constant evolutionary arms race with their pathogens. At the molecular level, the plant nucleotide-binding leucine-rich repeat receptors (NLRs) family has coevolved with rapidly evolving pathogen effectors.
Ethan J. Andersen +7 more
doaj +1 more source
Case report: a rare case of Hunter syndrome (type II mucopolysaccharidosis) in a girl
BMC Medical Genetics, 2019 Background Hunter syndrome (mucopolysaccharidosis type II) is a recessive X-linked disorder due to mutations in the iduronate 2-sulfatase (IDS) gene. The IDS gene encodes a lysosomal enzyme, iduronate 2-sulfatase. The disease occurs almost exclusively in
A. N. Semyachkina +9 more
doaj +1 more source
Id genes in nervous system development.
Histology and histopathology, 2000 Id genes encode helix-loop-helix proteins that function to mediate processes important for normal development including cellular differentiation, proliferation and apoptosis. Id proteins act as negative regulators of other transcription factors, which are essential for cell determination and differentiation in diverse cell types, and interact with ...
Andres-Barquin, P.J. +2 more
openaire +3 more sources
Rodent BC1 RNA gene as a master gene for ID element amplification. [PDF]
Proceedings of the National Academy of Sciences, 1994 ID elements are short interspersed repetitive DNA elements (SINEs) which have amplified in rodent genomes via retroposition, a process involving an RNA intermediate. BC1, an abundant ID-related transcript, is transcribed from a conserved, single-copy gene in rodents.
J, Kim +4 more
openaire +2 more sources
Large-scale event extraction from literature with multi-level gene normalization [PDF]
, 2013 Text mining for the life sciences aims to aid database curation, knowledge summarization and information retrieval through the automated processing of biomedical texts.
Ananiadou, Sophia +10 more
core +3 more sources
Detailed pedigree analyses and prenatal diagnosis for a family with mucopolysaccharidosis type II
BMC Medical Genomics, 2021 Background Mucopolysaccharidosis type II (MPS II) is an X-linked multisystem disorder caused by mutations in the gene encoding iduronate 2-sulfatase (IDS).
Chuan Zhang +13 more
doaj +1 more source