Results 41 to 50 of about 385,555 (227)
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
IPC-IG Relatório de Atividades 2019 [PDF]
, 2020 "The International Policy Centre for Inclusive Growth (IPC-IG) is pleased to present its 2019 Activity Report, outlining its research projects, knowledge products, and outreach activities conducted in the past year.
(IPC-IG), International Policy Centre for Inclusive Growth
core
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Quiemonis and the epichoric anthroponymy of Ig
Arheološki Vestnik, 2016 The main focus of the article is the personal name Q(u)iemoni(s), recently discovered on a tombstone found in the Church of sv. Janez Krstnik (St. John the Baptist) in Podkraj.
Luka Repanšek
doaj
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
, 2022 Additional file 4: Supplementary Fig. 3. IL-6 serum levels (A) and peripheral blood CD4posCD25posFoxP3high subset distribution (B) across 12 months follow-up in RA patients treated with CTLA4-Ig based on the achievement of DAS ...
Maria Rita Gigante (5591174) +6 more
core +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Aerosol and Air Quality Research, 2020 The COVID-19 outbreak measures of lockdown have generated exceptional urban behavior conditions allowing the analysis of a unique scenario. We examined the atmospheric emissions in Buenos Aires, Argentina, based on urban and industrial continuous ...
Natacha S. Represa +4 more
doaj +1 more source
, 2022 Additional file 3: Supplementary Fig. 2. ROC curves for IL-6 (A) and CD4posCD25posFoxP3pos cells rate (B) significantly distinguishing RA patients achieving DAS-defined remission at 6 months of CTLA4-Ig ...
Maria Rita Gigante (5591174) +6 more
core +1 more source
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source