IgA Antibodies and IgA Deficiency in SARS-CoV-2 Infection [PDF]
Frontiers in Cellular and Infection Microbiology, 2021 A large repertoire of IgA is produced by B lymphocytes with T-independent and T-dependent mechanisms useful in defense against pathogenic microorganisms and to reduce immune activation.
Isabella Quinti +4 more
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Clinical symptoms in IgA deficiency
Revista Alergia México, 2017 Background: IgA deficiency is the most common primary immunodeficiency. Early diagnosis and clinical follow-up may improve the quality of life of patients with IgA deficiency. To this end, IgA deficiency should be further studied and better understood on
Flavio Augusto De Oliveira-Serra +3 more
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Duodenal nodular lymphoid hyperplasia in a patient with IgA deficiency [PDF]
Clinical Case Reports, 2020 Most patients with IgA deficiency are asymptomatic, but duodenal nodular lymphoid hyperplasia is one symptom known to be associated with common variable immunodeficiency (CVID), including selective IgA deficiency and agammaglobulinemia.
Hanae Ida +5 more
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Selective IgA Deficiency [PDF]
Journal of Clinical Immunology, 2010 Immunoglobulin A (IgA) deficiency is the most common primary immunodeficiency defined as decreased serum level of IgA in the presence of normal levels of other immunoglobulin isotypes. Most individuals with IgA deficiency are asymptomatic and identified coincidentally.
Leman Yel, Yel, L, Yel, Leman
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A novel method to standardise serum IgA measurements shows an increased prevalence of IgA deficiency in young children with recurrent respiratory tract infections [PDF]
Clinical & Translational Immunology, 2021 Objectives While physicians are often confronted with immunoglobulin A (IgA) deficiency in children with recurrent infections, the clinical relevance of this finding is unclear. Large‐scale studies examining the significance of IgA deficiency in children
Mischa H Koenen +13 more
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Bifidobacterium-driven immunoglobulin A production in pediatric patients with IgA deficiency and recurrent respiratory tract infections [PDF]
MicrobiomeBackground Immunoglobulin A (IgA) deficiency is the most common primary antibody deficiency and contributes to recurrent respiratory tract infections (rRTIs) in children, with prevalence rates in this group ranging from 1:4 to 1:65.
Mischa H. Koenen +13 more
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Minimal-moderate variation of human oral virome and microbiome in IgA deficiency [PDF]
Scientific Reports, 2021 Immunoglobulin A (IgA) is the dominant antibody found in our mucosal secretions and has long been recognized to play an important role in protecting our epithelium from pathogens.
Maria José de la Cruz Peña +4 more
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IgG subclasses in symptomatic IgA deficiency
The Turkish Journal of Pediatrics, 1992 We evaluated IgG subclass levels in 11 symptomatic patients (ages between 3 and 22; mean 7.5 years) with IgA deficiency, seven with selective IgA deficiency, and four with low IgA levels.
I Tezcan, F Ersoy, O Sanal
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The clinical implications of selective IgA deficiency [PDF]
Journal of Translational Autoimmunity, 2019 Selective IgA deficiency (SIgAD) is the most common primary immunodeficiency but does not always result in clinical disease. This may in part be due to the definition based on serum IgA, while most IgA is secreted at mucosal surfaces, not amenable to ...
Samantha Swain +3 more
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Selective IgA Deficiency a Probable Risk of Recurrent Chest Infections in Asthmatics [PDF]
Journal of Asthma and Allergy, 2021 Fawzia Hassan Abo Ali,1 Nehal Elfawy Mahmoud,1 Amr Yakout Mohamed El-Sayed,1 Mariam Fathy Abdelmaksoud,2 Alaa K Shata,3 Shaimaa Hani Fouad1 1Department of Internal Medicine/Allergy and Clinical Immunology, Ain-Shams University, Cairo, Egypt; 2Department ...
Abo Ali FH +5 more
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