Results 191 to 200 of about 41,598 (251)

Autoimmunity and Periodontitis

Journal of Periodontal Research, EarlyView.
In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga, Vivek Thumbigere‐Math, Mark C. Herzberg   +2 more
wiley   +1 more source

Dupilumab in moderate‐to‐severe prurigo nodularis: Real‐world data from early access program

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Marie Jachiet, Clémentine Toussaint, Valérie Dorizy‐Vuong, Sophie Osdoit, Pierre‐André Becherel, Emmanuelle Amazan, Julia Vanlerberghe, Mahtab Samimi, Claudia Soares Barbosa, Carine Vera, Simmi Wiggins, Véronique Marcadé Fulcrand, Cédric Meyer, Laurent Misery, Jean‐David Bouaziz   +14 more
wiley   +1 more source

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Selective IgA deficiency

The Indian Journal of Pediatrics, 1982
Of 140 patients referred to the Pediatric Immunology Clinic during of 12-month period with the symptoms of recurrent infections or allergic respiratory illness, 21 (75%) were found to have selective IgA deficiency defined as serum concentration ≤ 5 mg. with normal levels of IgG and IgM.
S, Sahni, G, Woodford, R K, Chandra
openaire   +2 more sources

IgA deficiency

Current Opinion in Allergy & Clinical Immunology, 2012
To summarize recent publications on clinical and genetic aspects of IgA deficiency (IgAD).Both major histocompatibility complex (MHC) and non-MHC genes contribute to susceptibility to the disease. The former genes appear to be located in different parts of the MHC region depending on the HLA haplotype.
Ning, Wang, Lennart, Hammarström
openaire   +2 more sources

Endocrinopathy and IgA deficiency

Clinical Immunology and Immunopathology, 1973
Abstract Three cases of IgA deficiency occurring in association with endocrine hypofunction—Turner's syndrome, hypothyroidism, and diabetes—are described. The significance of IgA deficiency associated with chromosome abnormalities are discussed in view of the present finding of IgA deficiency in a patient with Turner's syndrome displaying a karyotype
H K, Silver, J, Shuster, P, Gold, D, Hawkins, S O, Freedman   +4 more
openaire   +2 more sources

Physiology of IgA and IgA Deficiency

Journal of Clinical Immunology, 2001
Although secretory immunoglobulin A (IgA) is important in mucosal immunity. selective IgA deficiency is the most common primary immunodeficiency of humans. In most cases this defect is not associated with any illness. The reasons for this are unknown, but other immunological compensations might provide sufficient or complete restitution. Alternatively,
openaire   +2 more sources

IgA deficiency in wolves

Developmental & Comparative Immunology, 2013
Low mean concentrations of serum immunoglobulin A (IgA) and an increased frequency of overt IgA deficiency (IgAD) in certain dog breeds raises the question whether it is a breeding-enriched phenomenon or a legacy from the dog's ancestor, the gray wolf (Canis lupus).
Marcel, Frankowiack, Lars, Hellman, Yaofeng, Zhao, Jon M, Arnemo, Miaoli, Lin, Katarina, Tengvall, Torsten, Møller, Kerstin, Lindblad-Toh, Lennart, Hammarström   +8 more
openaire   +2 more sources

FAMILIAL SELECTIVE IgA DEFICIENCY

Pediatrics, 1972
Thirteen subjects with selective IgA deficiency were obtained from five separate families. In three families an autosomal recessive inheritance was apparent while an autosomal dominant inheritance appeared very likely in the two remaining families. An increased incidence of quantitative defects in immunoglobulin synthesis was seen in ...
P A, Nell, A J, Ammann, R, Hong, E R, Stiehm   +3 more
openaire   +2 more sources