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Insight into the Interplay of Gd-IgA1, HMGB1, RAGE and PCDH1 in IgA Vasculitis (IgAV). [PDF]

open access: yesInt J Mol Sci
Held M   +8 more
europepmc   +1 more source
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IgA vasculitis

Seminars in Immunopathology, 2021
IgA vasculitis (IgAV) is an inflammation of small vessels caused by perivascular deposition of IgA and activation of neutrophils. It may present as systemic vasculitis (IgAV - Henoch-Schönlein purpura) or as a variant restricted to the skin (skin-limited IgAV), while IgA nephropathy presents a variant restricted to the kidneys.
Evangéline Pillebout   +1 more
openaire   +3 more sources

Intramuscular Hematoma as a Manifestation of IgA Vasculitis [PDF]

open access: bronzePediatrics, 2020
We describe an atypical pediatric case of immunoglobulin A vasculitis (IgAV), also referred to as Henoch-Schönlein purpura, in which formation of spontaneous hematoma of the paraspinal muscles developed. Spontaneous or unprovoked hematomas rarely occur in IgAV.
Wilson File, Sally Azer, Rianna Leazer
openaire   +3 more sources

IgA vasculitis nephritis

Current Opinion in Pediatrics, 2022
Purpose of review The purpose of this update is to summarize current knowledge on the pathophysiology of immunglobulin A (IgA) vasculitis nephritis (IgAVN) as well as to critically review evidence for established therapeutic regimes and available biomarkers. An additional purpose is to raise the discussion what could be done to
Eva, Nüsken, Lutz T, Weber
openaire   +2 more sources

Geospatial clustering of childhood IgA vasculitis and IgA vasculitis-associated nephritis

Annals of the Rheumatic Diseases, 2021
Research on spatial variability of the incidence of IgA vasculitis (IgAV) in children and its potential implications for elucidation of the multifactorial aetiology and pathogenesis is limited. We intended to observe spatial variability of the incidence of IgAV and IgA vasculitis-associated nephritis (IgAVN) using modern geostatistical methods, and ...
Mario Sestan   +11 more
openaire   +4 more sources

Interventions for preventing and treating kidney disease in IgA vasculitis.

Cochrane Database of Systematic Reviews, 2023
BACKGROUND IgA vasculitis (IgAV), previously known as Henoch-Schönlein purpura, is the most common vasculitis of childhood but may also occur in adults.
D. Hahn, E. Hodson, J. Craig
semanticscholar   +1 more source

Management of IgA Vasculitis with Nephritis

Pediatric Drugs, 2021
Immunoglobulin A (IgA) vasculitis (IgAV), previously called Henoch-Schönlein purpura, is characterized by IgA-dominant immune deposits affecting small vessels and often involves the skin, gastrointestinal tract, joints, and kidneys. IgAV is the most common cause of systemic vasculitis in children.
Jean-Daniel Delbet   +4 more
openaire   +3 more sources

Multisystemic manifestations of IgA vasculitis

Clinical Rheumatology, 2020
Immunoglobulin A vasculitis (IgAV), also known as Henoch-Schönlein Purpura, is one of the most common kind of systemic vasculitis in children, and due to the involvement of small blood vessels throughout the body, this disease can cause a variety of symptoms in different organs. Our aim was to review the data on various systemic manifestations of IgAV.
Lina Du   +5 more
openaire   +3 more sources

IgA Vasculitis in Adults

Current Treatment Options in Rheumatology, 2018
Immunoglobulin A vasculitis (IgAV) is a small vessel vasculitis with skin, joint, gastrointestinal and renal manifestations. Our understanding of the natural history of this disease is limited due to the overall low incidence of IgAV in adults and a lack of consensus regarding diagnostic criteria.
Heather N. Reich   +4 more
openaire   +2 more sources

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