Results 11 to 20 of about 56,897 (249)

AI in the drug discovery pipeline [PDF]

open access: yesAlzheimers Dement
Abstract Background Scientists spend vast amounts of resources and time to produce safe and effective treatments across a large range of diseases and symptoms. Often, 3 or more years are spent in drug discovery for compound screening and lead optimization. We show an AI model that accelerates the discovery process, thereby allowing researchers to reach
García N   +4 more
europepmc   +2 more sources

Multimodal Interpretable Transformer for AD [PDF]

open access: yesAlzheimers Dement
Abstract Background Artificial intelligence (AI) has significantly improved diagnostic accuracy in fields such as cancer, diabetes, and cardiopulmonary disease. It holds similar promise for Alzheimer’s disease (AD), where underdiagnosis remains a major challenge (false negatives = 11.9%). Addressing this requires models trained on diverse datasets that
Puentes P   +6 more
europepmc   +2 more sources

Early Prediction of MMSE & CSI‐D Scores with AI [PDF]

open access: yesAlzheimers Dement
Abstract Background We use Llama a LLM to predict MMSE and CSI‐D scores using socio economic data. The growing global burden of dementia needs improved early detection methods that account for diverse socioeconomic factors. While traditional machine learning approaches have been applied to predict cognitive status, they face limitations with complex ...
Crovo D   +4 more
europepmc   +2 more sources

Evaluation a volumetric water content sensor to be used for compacted filtered iron ore tailings [PDF]

open access: yesE3S Web of Conferences, 2023
The use of compacted landfills for filtered tailings has grown to replace dams. Considering that this is a structure that must remain in the unsaturated condition, it is necessary to monitor the flow pattern and water retention in these landfills.
Landim Ariane de Sá   +3 more
doaj   +1 more source

AVALIAÇÃO DA EVOLUÇÃO DO ÍNDICE GERAL DE CURSOS - IGC DAS INSTITUIÇÕES DE ENSINO SUPERIOR DE SANTA CATARINA

open access: yesRevista Gestão Universitária na América Latina, 2019
The competitiveness in the education sector makes Higher Education Institution (HEI) to be attentive to the quality of service they offer, aiming to maintain and win new students, partners or investors.
Cleber Cervi, Adriane Cervi Blümke
doaj   +1 more source

Longitudinal Analysis of Antibody Responses to the mRNA BNT162b2 Vaccine in Patients Undergoing Maintenance Hemodialysis: A 6-Month Follow-Up

open access: yesFrontiers in Medicine, 2021
Background: Patients on hemodialysis (HD) are at higher risk for COVID-19, overall are poor responders to vaccines, and were prioritized in the Portuguese vaccination campaign.Objective: This work aimed at evaluating in HD patients the immunogenicity of ...
André Weigert   +26 more
doaj   +1 more source

Kinetics of sharp intergranular corrosion fissures in AA7178 [PDF]

open access: yes, 2007
During service in structural aircraft applications, AA7178 has been found to develop sharp intergranular corrosion (IGC) fissures, a special form of attack.
Frankel, G. S., Huang, Tsai-Shang
core   +1 more source

Integrated Group of Companies as Subject of Public Policy by the Case of JSC «Gazprom-Media Holding»

open access: yesУправленческое консультирование, 2018
The author focuses on the consideration of the concept of integrated groups of companies by J. Pappe as an analytical tool for studying subjects of corporate interests and mechanisms of corporate representation in the political space of modern Russia. In
A. E. Kostin
doaj   +1 more source

Quantification of the Landscape for Revealing the Underlying Mechanism of Intestinal-Type Gastric Cancer

open access: yesFrontiers in Oncology, 2022
Gastric cancer is a daunting disease with a tragic impact on global health. It is the fourth most common cancer and has become the second most frequent cause of cancer death in recent times.
Chong Yu, Jin Wang
doaj   +1 more source

The modern versus extended evolutionary synthesis : sketch of an intra-genomic gene's eye view for the evolutionary-genetic underpinning of epigenetic and developmental evolution [PDF]

open access: yes, 2018
Studying the phenotypic evolution of organisms in terms of populations of genes and genotypes, the Modern Synthesis (MS) conceptualizes biological evolution in terms of 'inter-organismal' interactions among genes sitting in the different individual ...
Blancke, Stefaan   +2 more
core   +3 more sources

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