Results 31 to 40 of about 25,700 (219)

End-to-End Premature Ventricular Contraction Detection Using Deep Neural Networks

Sensors, 2023
In Holter monitoring, the precise detection of standard heartbeats and ventricular premature contractions (PVCs) is paramount for accurate cardiac rhythm assessment.
Dimitri Kraft, Gerald Bieber, Peter Jokisch, Peter Rumm   +3 more
doaj   +1 more source

Hyper-IgD Syndrome and pregnancy

European Journal of Obstetrics & Gynecology and Reproductive Biology, 1996
In this report two cases of the coincidence of hyperimmunoglobulinemia D syndrome (HIDS) and pregnancy are described. HIDS is not associated with complications in pregnancy or disturbance in fetal outcome; the frequency of attacks diminishes during pregnancy; HIDS probably inherits via an autosomal recessive trait and is not transmitted to children of ...
Hullu, J.A. de, Drenth, J.P.H., Struyk, A.P.H.B., Meer, J.W.M. van der   +3 more
openaire   +4 more sources

Interstitial Granulomatous Dermatitis (IGD)

Open Access Macedonian Journal of Medical Sciences, 2017
We report the case of a 42 years old male patient suffering from skin changes , which appeared in the last 7-8 years.  Two biopsies were performed during the evolution of the lesion. Both showed similar findings that consisted in a busy dermis with interstitial, superficial and deep infiltrates of lymphocytes and histiocytes dispersed among collagen ...
Tebeica, Tiberiu (author), Voicu, Cristiana (author), Patterson, James W. (author), Mangarov, Hristo (author), Lotti, T. (author), Wollina, Uwe (author), Lotti, Jacopo (author), França, Katlein (author), Batashki, Atanas (author), Tchernev, Georgi (author)   +9 more
openaire   +5 more sources

Optimization of B Cell Responses in Human Immune System Mice Through Organoid Based Screening

Advanced Science, EarlyView.
Human immune system (HIS) mice show limited B cell responses to immunization. Using HIS mouse spleen organoids, this study identifies cytokine combinations and innate immune signals that drive human B cell expansion, differentiation, and class‐switch. Applying these signals in vivo through temporal separation enables antigen‐specific IgG responses and ...
Haiqiao Sun, He Li, Xu Zhu, Zijian Zhang, Deshan Ren, Shuai Ding, Yan Li   +6 more
wiley   +1 more source

SOX5 Orchestrates Malignant Evolution via Promoter‐Centric Chromatin Remodeling in MYC‐Driven B‐Cell Lymphoma

Advanced Science, EarlyView.
In MYC‐enforced B‐cell lymphoma, SOX5 occupies promoter‐proximal regulatory regions and is associated with reduced chromatin accessibility at the PCNP locus. PCNP repression promotes proliferative remodeling by limiting apoptosis and cell‐cycle restraint.
Yiyou Mao, Zhenyuan Jia, Xiao‐Qin Mu, Ruilin Wang, Jianli Ma, Qingyuan Zhang, Yuwei Deng   +6 more
wiley   +1 more source

6D Strawberry Pose Estimation: Real-time and Edge AI Solutions Using Purely Synthetic Training Data [PDF]

ISPRS Annals of the Photogrammetry, Remote Sensing and Spatial Information Sciences
Automated and selective harvesting of fruits is increasingly vital due to high costs and seasonal labor shortages especially in advanced economies. This paper focuses on 6D pose estimation of strawberries using purely synthetic data generated through a ...
S. N. Sinha, P. J. Kühn, M. S. Goschke, M. Weinmann   +3 more
doaj   +1 more source

Molecular Dynamics‐Guided Sterol Engineering of mRNA‐Lipid Nanoparticles Reprograms Biodistribution and Enhances Spleen‐Selective Immunity

Advanced Science, EarlyView.
Sterol engineering enables precise control of mRNA lipid nanoparticles by tuning membrane organization. Replacing cholesterol with bile acid‐derived sterols redirects protein expression from the liver to the spleen. Notably, CA‐20 LNP enhances antigen‐specific immune responses while exhibiting a favorable safety profile, highlighting sterols as a ...
Sanghyuk Jeon, Seo‐Hyeon Bae, Jungyong Ji, Jisun Lee, Hosam Choi, Min‐Ho Kang, Sang‐In Park, Hyemin Kim, Nakyung Lee, Hajin Lee, Seonghoon Kim, Jungmin Kim, Subin Yoon, Seonghyun Lee, Seongje Cho, Dahyeon Ha, Ayoung Oh, Sohee Jo, Huijeong Choi, Yeeun Lee, Sowon Lee, Hyo‐Jung Park, Gitak Nam, Jisu Shin, Yujin Kang, Wonpil Im, Kiyoun Lee, Jae‐Hwan Nam   +27 more
wiley   +1 more source

B Cells are Activated via a Nanoporous Interface that Stabilizes Microvilli and Engages Mechanosensitive Ion Channels

Advanced Science, EarlyView.
B cells can be activated independently of antigen recognition via mechanical stimulation through nanoporous substrates. Exposure to such substrates induced B cell microvilli extension into the pores, intracellular Ca2+ signaling, phosphorylation of signaling proteins, and CD69 expression.
Nozie D. Aghaizu, Willi Weber, Nadine Strempel, Asya Polat, Enrico Klotzsch   +4 more
wiley   +1 more source

Age‐associated immune dysregulation links to disease severity in macrolide‐resistant Mycoplasma pneumoniae pneumonia: Insights from a comparative juvenile–adult mouse model

Animal Models and Experimental Medicine, EarlyView.
Macrolide‐resistant Mycoplasma pneumoniae (MRMP) infected both juvenile and adult mice, with results compared to normal juvenile mice. The findings revealed comparable bacterial loads between juvenile and adult mice, yet juvenile mice exhibited more severe lung damage and elevated levels of inflammatory cytokines.
Xuejun Li, Yudong Wang, Liyong Liu, Mengmeng Gong, Jinlong Wang, Yuqing Cao, Zhixin Sun, Fanliang Meng, Qiuyan Wang, Hongji Wu, Fei Zhao, Yan Ma, Yibai Xiong   +12 more
wiley   +1 more source

NY-GATHER: A Benchmark for Urban Gathering Event Detection and Forecasting

IEEE Access
The effective detection of urban gathering events, such as concerts, festivals, and sports events, is vital due to the potential impact they can have on city residents and infrastructure.
Daniel Fahrmann, Malte Ihlefeld, Florian Kirchbuchner, Naser Damer   +3 more
doaj   +1 more source