Results 31 to 40 of about 232,932 (206)

Allergic Aspects of IgG4-Related Disease: Implications for Pathogenesis and Therapy

Frontiers in Immunology, 2021
IgG4-related disease (IgG4-RD) is a rare systemic fibroinflammatory disease frequently associated with allergy. The pathogenesis of IgG4-RD is poorly understood, and effective therapies are limited.
Despina Michailidou, Daniella Muallem Schwartz, Tomas Mustelin, Grant C. Hughes   +3 more
doaj   +1 more source

Recent Progress on the Roles of Regulatory T Cells in IgG4-Related Disease

Immuno, 2022
IgG4-related disease (RD) is a proposed concept of systemic inflammatory condition from Japanese researchers. Patients with IgG4-RD manifest several immunological and histological characterizations in the organs involved, including elevated levels of ...
Kazushige Uchida
doaj   +1 more source

Serum immunoglobulin free light chains and their association with clinical phenotypes, serology and activity in patients with IgG4-related disease

Scientific Reports, 2021
The clinical utility of serum immunoglobulin free light chains (sFLC) in IgG4-related disease (IgG4-RD) is unknown. Herein we evaluated their association with clinical phenotypes, serology and activity in patients with IgG4-RD. Cross-sectional study that
Eduardo Martín-Nares, Vanessa Saavedra-González, Reynerio Fagundo-Sierra, Blanca Estela Santinelli-Núñez, Teresa Romero-Maceda, Karla Calderón-Vasquez, Gabriela Hernandez-Molina   +6 more
doaj   +1 more source

The 2020 revised comprehensive diagnostic (RCD) criteria for IgG4-RD [PDF]

Modern Rheumatology, 2021
IgG4-related disease (IgG4-RD) is a fascinating clinical entity first reported in this century in Japan, and includes a wide variety of diseases, such as formerly named Mikulicz's disease (MD), autoimmune pancreatitis (AIP), interstitial nephritis, prostatitis and retroperitoneal fibrosis.
Hisanori, Umehara, Kazuichi, Okazaki, Shigeyuki, Kawa, Hiroki, Takahashi, Hiroshi, Goto, Shoko, Matsui, Nobukazu, Ishizaka, Takashi, Akamizu, Yasuharu, Sato, Mitsuhiro, Kawano   +9 more
openaire   +2 more sources

Natural history and pathogenesis of IgG4-related disease [PDF]

, 2015
IgG4-related disease (IgG4-RD) is a systemic fibro-inflammatory condition characterised by elevated serum IgG4 and an abundance of IgG4 plasma cells in involved organs.
Culver, Emma L, Emma L Culver
core   +1 more source

402. IgG4-RD and malignancy: Causal relationship or co-occurrence?

, 2022
Background/ Objectives: IgG4-related disease (IgG4-RD) is a systemic immune-mediated disease with tumefactive lesions [1]. IgG4-RD sometimes presents with malignancy-like symptoms and may be mistaken for cancer or can be seen together with cancer ...
Gözde Kübra Yardımcı1,2,
core   +1 more source

Increased Circulating Th1 and Tfh1 Cell Numbers Are Associated with Disease Activity in Glucocorticoid-Treated Patients with IgG4-Related Disease

Journal of Immunology Research, 2020
Background. This study is aimed at exploring the changes and significance of circulating Th and Tfh cell subsets in glucocorticoid-treated IgG4-RD patients. Methods.
Changsheng Xia, Caoyi Liu, Yanying Liu, Yan Long, Lijuan Xu, Chen Liu   +5 more
doaj   +1 more source

THU0588 CLINICAL PHENOTYPES OF IGG4-RELATED DISEASE IN SPAIN [PDF]

, 2019
Background: Recently, several clinical phenotypes in IgG4-related disease have been described in a multinational and ethnically variate cohort1. Objectives: To assess the clinical presentation of IgG4-related disease (IgG4-RD) in Spanish patients and ...
Iago Carballo, Blanca Pinilla, Toledano-Macias, M., María Toledano-Macías, Andreu Fernandez-Codina, De Miguel-Campo, B., Martinez-Valle, F., Luis Sáez-Comet, José Hernández-Rodríguez, Saez-Comet, L., Fernandez-Codina, A., Carballo Fernández, Iago, Fernando Martínez-Valle, Borja De Miguel-Campo, Hernandez-Rodriguez, J., Pinilla, B.   +15 more
core   +1 more source

Distinct metabolic biomarkers to distinguish IgG4-related disease from Sjogren’s syndrome and pancreatic cancer and predict disease prognosis

BMC Medicine, 2022
Background The pathogenesis of immunoglobulin G4-related disease (IgG4-RD) remains unclear. IgG4-RD often mimics other diseases, including pancreatic cancer (PC) and Sjogren’s syndrome (SS), which may easily lead to misdiagnosis. This study was performed
Songxin Yan, Yu Peng, Ziyan Wu, Linlin Cheng, Haolong Li, Honglin Xu, Yuan Huang, Wen Zhang, Yongzhe Li   +8 more
doaj   +1 more source

IgG4-related disease; a unifying entity [PDF]

Journal of Nephropharmacology, 2018
IgG4-related disease (IgG4-RD) is characterized by dense lymphoplasmacytic infiltration of different organs and elevated serum IgG4 level. The disease involves different organs including pancreas, kidney, aorta, lung, thyroid, salivary and lacrimal ...
Mohammadreza Ardalan, Kasra Ardalan
doaj   +1 more source