Results 231 to 240 of about 48,471 (314)

The Proinflammatory Secretome of Senescent Cells Can Be Controlled by a HIF2A‐Dependent Upregulation and a FURIN‐Dependent Cleavage of the ANGPTL4 Secreted Factor

Aging Cell, Volume 25, Issue 1, January 2026.
This article supports that ANGPTL4 secreted factor is induced transcriptionally and activated by proteolytic cleavage during senescence, contributing to the production of a pro‐inflammatory SASP. In the senescent cell microenvironment, ANGPTL4 could thus contribute to senescence‐dependent alterations such as inflammation and tumor initiation.
Gabriela Makulyte, Hasan Safwan‐Zaiter, Delphine Goehrig, Anda Huna, Adèle Mangelinck, Takumi Mikawa, Alberta Palazzo, Lyvia Moudombi, Jean‐Jacques Medard, Marie Chanal, Pacôme Lecot, Marie‐Cécile Michallet, Julie Gavard, Serge Adnot, Pierre Dubus, Hiroshi Kondoh, Carl Mann, Nguan Soon Tan, Philippe Bertolino, Jean‐Michel Flaman, David Bernard   +20 more
wiley   +1 more source

IgG4-Related Disease: Endocrine Involvement, Clinical Implications, and Management Strategies. [PDF]

Discoveries (Craiova)
Mohamed MA, Hammoud A, Jaber HM, Shaban LN, Shaqra LA, Nazzal LA, Haddadin DE, Haddadin FE, Alaqtash NM, Ahmed LEM, Sujith A.   +10 more
europepmc   +1 more source

Modulation of Cellular, Molecular, and Humoral Responses by PQ Grass 27,600 SU for the Treatment of Seasonal Allergic Rhinitis: A Randomised Double Blind Placebo Control Exploratory Field Study

Allergy, Volume 81, Issue 1, Page 232-247, January 2026.
The aim of the study is to interrogate immunological mechanisms induced by PQ Grass conventional and extended regimens. A short‐course pre‐seasonal subcutaneous injection of PQ Grass is effective in inducing immune tolerance by generating functional blocking antibodies and modulating T cell compartments.
Janice A. Layhadi, Sviatlana Starchenka, Pieter‐Jan De Kam, Elizabeth Palmer, Lily Y. D. Wu, Sean T. Keane, William T. Fulton, Prista Hikmawati, Xun Meng, Paulina Filipaviciute, Anna Cutrina Pons, Kemi Oluwayi, Katarzyna Lis, Oliver Armfield, Murray A. Skinner, Matthew D. Heath, Simon J. Hewings, Matthias F. Kramer, Mohamed H. Shamji   +18 more
wiley   +1 more source

IgG4-Related Disease Associated With Myotonic Dystrophy Type 2. [PDF]

Eur J Neurol
Pegat A, Svahn J, Gerfaud-Valentin M, Durel CA, Durupt S, Bernard E.   +5 more
europepmc   +1 more source

Pericardial Involvement in IgG4-related Disease

, 2015
Kiyoo Mori, Kazunori Yamada, Tetsuo Konno, Dai Inoue, Yoshihide Uno, M. Watanabe, Miho Okuda, Kotaro Oe, Mitsuhiro Kawano, Masakazu Yamagishi   +9 more
openalex   +2 more sources

Complete Remission of Advanced Hepatocellular Carcinoma Treated with Sorafenib and Concomitant Appearance of IgG4- related Diseases. A Case Report

, 2020
Giovanna Impellizzeri, Matteo Renzulli, Francesco Azzaroli, Rita Golfieri, G. Mazzella, Giovanni Marasco   +5 more
openalex   +2 more sources

Primary Antibody Deficiency in Patients With Chronic Rhinosinusitis: A Call for Immunologic Evaluation Prior to Biologic Therapy

Clinical Otolaryngology, Volume 51, Issue 1, Page 144-152, January 2026.
ABSTRACT Objective Chronic rhinosinusitis (CRS) is prevalent and causes a great negative impact on quality of life. Primary antibody deficiency (PAD) is highly prevalent with CRS compared to the background population. There are efficient treatment options to consider when CRS is a symptom of PAD. The condition seems to be underdiagnosed.
Anita García Petersen, Kasra Zainali‐Gill, Carsten Schade Larsen, Christian Nielsen, Therese Ovesen   +4 more
wiley   +1 more source

New Developments in the Treatment of IgG4-Related Disease: A Comprehensive Clinical Approach. [PDF]

J Clin Med
González-García A, Starita-Fajardo G, Lucena López D, Iranzo Alcolea MP, López-Paraja M, Peña-Rodríguez M, Lirola Sánchez F, Sánchez M, Viteri-Noël A, Fabregate-Fuente M, López-Rodríguez M, Calleja-López JL, Manzano Espinosa L.   +12 more
europepmc   +1 more source

Core Needle Biopsies in Patients With Lymphoproliferative Malignancies: An Observational Single‐Center Cohort Study

European Journal of Haematology, Volume 116, Issue 1, Page 85-92, January 2026.
ABSTRACT In the diagnostic evaluation of suspected lymphoma, both core needle biopsy (CNB) and surgical excisional biopsy (SEB) are routinely employed for tissue sampling. While SEB remains the gold standard, CNB is a less invasive and more cost‐effective alternative. However, concerns persist regarding its diagnostic yield.
Blas Holger Mogensen, Torsten Holm Nielsen, Mette Ølgod Pedersen, Lise Mette Rahbek Gjerdrum, Tarec Christoffer El‐Galaly, Lars Møller Pedersen   +5 more
wiley   +1 more source

Biopsy-Proven Cerebral Parenchymal Involvement in IgG4-Related Disease: A Case Report and a Literature Review. [PDF]

Cureus
Nakajima R, Takeda N, Okubo M, Asako K, Kikuchi H, Saito K, Numakura S, Sasajima Y, Kono H.   +8 more
europepmc   +1 more source