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IgG4-related disease

Revista Española de Medicina Nuclear e Imagen Molecular (English Edition), 2021
IgG4-related disease (ER-IgG4) is a recognised systemic disease. It was described after patients diagnosed with autoimmune pancreatitis showed signs of extra-pancreatic disease. The clinical manifestation of these patients is subacute and is manifested by the appearance of pseudotumoral lesions, or inflammatory or fibrous tumours.
M, Simó-Perdigó, F, Martinez-Valle
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IgG4-related disease

Joint Bone Spine, 2014
The term "IgG4-related disease" encompasses several disorders described many years ago under various designations depending on the organ or system involved (e.g., Mikulicz syndrome, Riedel's thyroiditis, and retroperitoneal fibrosis). The clinical presentation varies widely, as one or more organs may be affected, usually in the same region of the body ...
Elisabeth, Palazzo   +2 more
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IgG4-Related Kidney Disease

Clinical Journal of the American Society of Nephrology, 2023
The term “IgG4-related disease” was recently coined to identify a rare systemic disorder hallmarked by fibro-inflammatory, tumor-like masses possibly affecting almost any organ. Pathologic tissues are characterized by dense, polyclonal, lymphoplasmacytic infiltrates, rich in IgG4-positive plasma cells on a background of fibrosis, which often has a ...
Francesco Peyronel, Augusto Vaglio
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IgG4-related diseases

Best Practice & Research Clinical Rheumatology, 2012
Immunoglobulin G4 (IgG4)-related disease (IgG4-RD) is a fascinating condition recognised as a systemic disease in 2003 [1,2]. The first link between autoimmunity affecting the pancreas, elevated serum IgG4 concentrations and large numbers of IgG4-positive plasma cells in pancreatic tissue was described only 2 years earlier [3].
Monica, Guma, Gary S, Firestein
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IgG4-related orbital disease

Archivos de la Sociedad Española de Oftalmología (English Edition), 2018
The case is presented of a 64-year-old woman with bilateral palpebral swelling and dacryoadenitis, exophthalmos, and a history of chronic rhinitis and asthma. An increase in serum IgG4 was observed, and an incisional biopsy of lacrimal glands was performed, which showed fibrosis and a lymphoplasmacytic infiltrate with IgG4 producing cells.Orbital ...
J, Flores Balverdi   +5 more
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IgG4‐related skin disease

British Journal of Dermatology, 2014
IgG4-related disease (IgG4-RD) is a recently established clinical entity characterized by high levels of circulating IgG4, and tissue infiltration of IgG4(+) plasma cells. IgG4-RD exhibits a distinctive fibroinflammatory change involving multiple organs, such as the pancreas and salivary and lacrimal glands. The skin lesions of IgG4-RD have been poorly
Y, Tokura   +7 more
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IgG4-Related Disease

2016
IgG4-related disease (IgG4-RD) is a fibro-inflammatory condition characterized by fibrous swelling of affected organs, elevated serum IgG4 concentration in the majority of patients, and a prompt response to corticosteroid therapy. The concept of IgG4-RD as a novel clinical entity emerged at the beginning of the twenty-first century, when Hamano and ...
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IgG4-related disease

Assam Journal of Internal Medicine, 2019
© 2019 Immunoglobulin (Ig) G4-related disease is an immune-mediated fibro-inflammatory condition that can involve virtually every organ system. Our knowledge and understanding of this condition has expanded rapidly over the last decade, with insights into adaptive and innate immunological mechanisms, identification of novel risk factors, definition of ...
Emma L. Culver   +3 more
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