Recurrent C. difficile in a Patient with IgG Deficiency [PDF]
IgG deficiency can predispose to recurrent pyogenic infections. The association of IgG deficiency with Clostridium difficile infection has been infrequently reported in the literature.
Asad Jehangir +7 more
doaj +4 more sources
Factors associated with IgG levels in adults with IgG subclass deficiency [PDF]
Background Factors associated with IgG levels in adults with IgG subclass deficiency (IgGSD) are incompletely understood. We studied adults with IgGSD with subnormal IgG1 only, subnormal IgG1/IgG3, or subnormal IgG3 only without other subnormal IgG ...
James C. Barton +3 more
doaj +5 more sources
Immunoglobulin G subclass deficiency has been diagnosed in 25% of patients presenting with recurrent infections. Similar to other primary immunodeficiencies, it is commonly overlooked or misdiagnosed. The diagnosis includes documentation of a decreased level of one or more subclasses in conjunction with an inadequate response to a vaccine challenge ...
Russell M. Petrak, russell petrak
openalex +2 more sources
The impact of IgG subclass deficiency on the risk of mortality in hospitalized patients with COPD [PDF]
Background Immunoglobulin G (IgG) deficiency increases the risk of acute exacerbations and mortality in chronic obstructive pulmonary disease (COPD). However, the impact of IgG subclass deficiency on mortality in COPD is unknown.
Hyun Lee +7 more
doaj +2 more sources
Pathogenicity of Anti-ADAMTS13 Autoantibodies in Acquired Thrombotic Thrombocytopenic Purpura [PDF]
Background: Acquired thrombotic thrombocytopenic purpura (TTP) is an autoimmune disease in which anti-ADAMTS13 autoantibodies cause severe enzyme deficiency.
Mari R. Thomas +3 more
doaj +4 more sources
Does the Maternal Serum IgG Level during Pregnancy in Primary Antibody Deficiency Influence the IgG Level in the Newborn? [PDF]
Purpose. To find out if the serum IgG level in the newborn baby was affected by low maternal serum IgG during pregnancy in two newly diagnosed primary antibody deficient patients. Method.
Vasantha Nagendran +2 more
doaj +2 more sources
IgG subclasses in symptomatic IgA deficiency
We evaluated IgG subclass levels in 11 symptomatic patients (ages between 3 and 22; mean 7.5 years) with IgA deficiency, seven with selective IgA deficiency, and four with low IgA levels.
I Tezcan, F Ersoy, O Sanal
doaj +2 more sources
Primary vs. Secondary Antibody Deficiency: Clinical Features and Infection Outcomes of Immunoglobulin Replacement [PDF]
Secondary antibody deficiency can occur as a result of haematological malignancies or certain medications, but not much is known about the clinical and immunological features of this group of patients as a whole. Here we describe a cohort of 167 patients
AA Bousfiha +55 more
core +23 more sources
IFNAR1-Signalling Obstructs ICOS-mediated Humoral Immunity during Non-lethal Blood-Stage Plasmodium Infection [PDF]
Funding: This work was funded by a Career Development Fellowship (1028634) and a project grant (GRNT1028641) awarded to AHa by the Australian National Health & Medical Research Council (NHMRC).
A Haque +89 more
core +14 more sources

