Results 251 to 260 of about 259,280 (346)

Vitamin D Status, CMV Seropositivity, and Viral Cytokine Expression in Pregnancy. [PDF]

Viruses
Martins AD, Woo J, Falley B, Spencer JV.
europepmc   +1 more source

Older female mice lacking triggering recepter expressed on myeloid cells-2 have worse post-stroke neurological function and enhanced pro-inflammatory responses [PDF]

, 2019
Hsieh, C, Kacimi, R, Kurisu, K, Yenari, MA, Zheng, Z   +4 more
core  

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

Advanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou, Weijie Yang, Na Liu, Qing Liu, Jiamin Jin, Chenqiong Zhao, Xiaoying Jin, Miao Gui, Haiyan Zhu, Songying Zhang, Yinli Zhang   +10 more
wiley   +1 more source

Clinical and immunological spectrum of MHC class I deficiency: insights from a long-term cohort with two novel mutations. [PDF]

Front Immunol
Haskologlu S, Ikinciogullari A, Islamoglu C, Bal SK, Bayrakoglu D, Erdem S, Karahan ZC, Ardeniz O, Aytekin C, Heper A, Ceylaner S, Dogu F.   +11 more
europepmc   +1 more source

Interactions of Antibody Drug Conjugate Anti‐Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

Advanced Science, EarlyView.
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance, Bryan S. Yung, Michael M. Allevato, Marcus M Cheng, Maria F. Camargo, Robert Saddawi‐Konefka, Kanika Dhawan, Ashwyn K. Sharma, Mahsa Mortaja, Sophie Bice, Daniel J. Scanderbeg, Diego Alvarado, Jyoti Mayadev, Ramez N. Eskander, Stephen R. Adams, Pippa F. Cosper, J. Silvio Gutkind, Sunil J. Advani   +17 more
wiley   +1 more source

Vitamin D3 status and seroprevalence of Toxoplasma gondii in reproductive-aged women in Northern Iran. [PDF]

BMC Womens Health
Tork M, Sadeghi M, Sarvi S, Khazaei F, Basirpour B, Ahmadi S, Shariatzadeh SA, Hosseini SA, Zamaniyan M, Daryani A, Aghayan SA.   +10 more
europepmc   +1 more source

Patients with IgG subclass and/or selective antibody deficiency to polysaccharide antigens: Initiation of a controlled clinical trial of intravenous immune globulin

, 1989
Alan P. Knutsen
openalex   +1 more source

Modifying Glucose Metabolism Reverses Memory Defects of Alzheimer's Disease Model at Late Stages

Advanced Science, EarlyView.
Using spatial transcriptomics, we show that ferul enanthate (SL‐ZF‐01) reverses episodic‐like memory deficits in aged, but not young, Alzheimer’s disease (AD) mice. SL restores glucose metabolism and Glucose Transporter 1/3 expression via an ‘Aging‐AD‐Rescue’ pattern, rescuing deficits seen in aged AD mice.
Fang Liu, Yiyu‐Li Tang, Zong‐Bo Zhang, Ya‐Hong Tan, Si‐Hui Lin, Ni‐Ya Wang, Jin‐Nan Li, Zhi‐Jie Pan, Jian‐Feng Li, Jing‐Fei Huang, Yu‐Qiang Ding, Chun‐Ming Guo, Lin Xu, Cheng Peng, Qi‐Xin Zhou   +14 more
wiley   +1 more source

IgD in nucleus of pro-B cells promotes pro-B cells proliferation by regulating E2F3 expression. [PDF]

Cell Biosci
Zhang Y, Hou Y, Yu M, Zhang X, Zhang S, Zhu Z, Xu W, Huang J, Qiu X.   +8 more
europepmc   +1 more source

Imbalanced serum IgG subclass pattern in toxic shock syndrome patients: deficiency of specific IgG1 and IgG4 subclass antibodies to toxic shock syndrome toxin 1.

, 1986
Bértil Christensson, Hugo Johansson, Vivi‐Anne Oxelius   +2 more
openalex   +1 more source