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IgG subclass deficiency

The Pediatric Infectious Disease Journal, 1990
Although the occurrence of selective deficiencies of serum IgG subclasses has been known for 20 years, the large body of data presently available was collected only recently owing to the use of performing monoclonal antibodies. IgG subclass deficiency is frequent, both as an apparently isolated defect (about one fourth of patients suffering otherwise ...
J L, Preud'homme, L A, Hanson
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IgG Subclass Deficiencies

Vox Sanguinis, 1986
Abstract. IgG subclasses differ not only in their biochemical and biologic properties, but also in their occurrence as selective deficiencies, alone and in combination. The normal range of IgG subclass concentrations in children and adults is compared with deficiencies found in individuals with repeated respiratory tract infections.
L A, Hanson   +5 more
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IgG subclass deficiency

Pediatric Allergy and Immunology, 1991
The different biological properties of human IgG subclasses make each subclass unique in its functional role in either resistance to infection, autoimmune diseases or allergy. Not only are there marked differences in the relative concentrations of IgG subclasses in serum (IgG1> IgG2> IgG3/IgG4) but the distribution of the antibody responses in ...
A. Ferrante, L. J. Beard, D. M. Roberton
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IgG subclass deficiency with or without IgA deficiency

Clinical Immunology and Immunopathology, 1991
IgG subclass deficiency (IgGSD) is difficult to define since reference materials vary between laboratories and the clinically relevant cut off levels for the various subclasses are not well known. The diagnosis of IgGSD should be based on more than one determination since the levels vary, due to various factors such as infections, operations, etc ...
L A, Hanson   +7 more
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Molecular basis of IgG subclass deficiency

Immunological Reviews, 2000
IgG subclass deficiency was recognized as a separate disease entity in the early seventies and was shown to be associated with an increased susceptibility to infections. Although deletions of the corresponding gamma genes have been demonstrated in a few cases, a majority of patients suffer from a regulatory dysfunction, and the deficiencies are most ...
Q, Pan, L, Hammarström
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IgG Subclasses in Selective IgA Deficiency

New England Journal of Medicine, 1981
A SELECTIVE deficiency in IgA appears in about one in 700 persons.1 Many of these persons are healthy,2 but there is an increased frequency of infections, autoimmune disorders, atopy, and malabsorp...
V A, Oxelius   +6 more
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IgG immunoglobulin deficiency in muscular dystrophic chickens

Journal of Heredity, 1977
Plasma immunoglobulin profiles of New Hampshire strain muscular dystrophic chickens were determined by radial immunodiffusion, immunoelectrophoresis and polyacrylamide gel electrophoresis. Muscular dystrophic chickens have reduced levels of IgG but maintain normal levels of total serum proteins, IgA and IgM. The relationship and significance of the IgG
B G, Sanders, K, Kline
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IgG subclass deficiency in amyotrophic lateral sclerosis

Acta Neurologica Scandinavica, 2009
In order to get to clues about T-cell independent versus T-cell dependent immune mechanism in ALS, we measured IgG subclasses in 25 ALS-patients: 16 patients had deficiency of T-cell dependent expressed IgG1 or IgG3 or both with essentially normal levels of T-cell independent expressed IgG2 and IgG4.
B, Ostermeyer-Shoaib, B M, Patten
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Chronic glomerulonephritis associated with IgG subclass deficiency

Pediatric Nephrology, 2007
We experienced two patients with IgG subclass deficiency who suffered from chronic glomerulonephritis (GN). Patient 1 was a 17-year-old girl with IgG subclass deficiency (combined deficiency of IgG2 and IgG4). Renal biopsy was performed when she was aged 16 years, and she was diagnosed with membranoproliferative GN.
Koichi, Kamei   +6 more
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IgG deficiency in association with placental oedema

Early Human Development, 1977
Deficiency of the immunoglobulin C (IgG) in the human newborn is rare in the absence of maternal hypogammaglobulinaemia. Low concentrations of IgG in cord blood were found in 3 conditions--the donor twin in the fetofetal transfusion syndrome, hydrops fetalis and congenital hepatic disease. These were all associated with placental oedema.
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