Results 71 to 80 of about 252,713 (344)

Intradermal immunization with wall teichoic acid (WTA) elicits and augments an anti-WTA IgG response that protects mice from methicillin-resistant Staphylococcus aureus infection independent of mannose-binding lectin status. [PDF]

PLoS ONE, 2013
The objectives of this study were to investigate the immune response to intradermal immunization with wall teichoic acid (WTA) and the effect of MBL deficiency in a murine model of infection with methicillin-resistant Staphylococcus aureus (MRSA). WTA is
Kazue Takahashi, Kenji Kurokawa, Patience Moyo, Dong-Jun Jung, Jang-Hyun An, Lorencia Chigweshe, Elahna Paul, Bok Luel Lee   +7 more
doaj   +1 more source

496 Partial immunoglobulin deficiency in association with IgG subclass deficiency

Journal of Allergy and Clinical Immunology, 1991
Donald McNeil, Paul R. Sanberg, Richard J. Lamont   +2 more
openalex   +3 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Audit of immunoglobulin monitoring and hypogammaglobulinaemia after B cell targeted therapy in a paediatric cohort in a high immune disease prevalence Region

Clinical Medicine
Introduction: Secondary hypogammaglobulinaemia or antibody deficiency (SAD) is an under-recognised complication of B cell-targeted therapies (BCTTs) in both autoimmune diseases (AIDs) and haematological malignancy.
Khadija Karim, Omar Mostafa, Alaa Samarh, Sharon Bout-Tabaku, Buthaina Al-Adba, Ahmad Kaddourah, Abubakr Imam, Ibrahim Shatat, Bajes Hamad, Mahmoud Fawzi, Ruba Benini, Ayman Saleh, Tayseer Yousif, Areeg Ahmed, Yasmin El Bsat, Bernice Lo, Mohammed Yousuf Karim   +16 more
doaj   +1 more source

Salmonella typhi vaccination response study reveals defective antibody production selective IgA deficiency patient

Revista Alergia México, 2015
Selective IgA deficiency (SIgAD) is the most prevalent immunodeficiency worldwide, progressing to common variable immunodeficiency only in few reported cases.
Daniel E Pleguezuelo, Carla Gianelli
doaj   +1 more source

COVID-19 Recurrence Without Seroconversion in a Patient With Mannose-Binding Lectin Deficiency

Allergy & Rhinology, 2021
Introduction The SARS-CoV-2 virus has infected more than 63,000,000 people worldwide after emerging from Wuhan, China in December 2019. This outbreak was declared a Public Health Emergency in January 2020, and a pandemic in March. While rare, reinfection
Breanne Hayes DO, Jonathan Stanley DO, Brian P. Peppers DO, PhD   +2 more
doaj   +1 more source

A mutation in caspase-9 decreases the expression of BAFFR and ICOS in patients with immunodeficiency and lymphoproliferation [PDF]

, 2015
Lymphocyte apoptosis is mainly induced by either death receptor-dependent activation of caspase-8 or mitochondria-dependent activation of caspase-9. Mutations in caspase-8 lead to autoimmunity/lymphoproliferation and immunodeficiency. This work describes
Boggio, E, Cappellano, G, Chiocchetti, A., Clemente, N, Dianzani, C, Dianzani, I, Dianzani, U, Gigliotti, Cl, Notarangelo, Ld, Orilieri, E, Pignata, C, Quinti, Isabella, Ramenghi, U, Santoro, C, Toth, E, Valletti, Pa   +15 more
core   +2 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

CONCENTRATIONS OF IgG SUBCLASSES IN ALLOGENEIC BONE MARROW RECIPIENTS

Медицинская иммунология, 2014
A sufficient increase of infectious complications rate during early posttransplant period in allogeneic bone marrow (allo-BM) recipients has been traditionally explained by the prominent drop of serum IgG levels in the patients.
A. V. Klimovich, M. T. Van Lint, M. P. Samoilovich, B. V. Afanasiev, V. B. Klimovich   +4 more
doaj   +1 more source

Chapter Five. Systematic review results by biomarker classifications [PDF]

, 2016
5.1 Markers of Absorption and Permeability Overview 5.2 Markers of Absorption 5.3 Markers of Permeability 5.4 Markers of Digestion 5.5 Markers of Intestinal Inflammation and Intestinal Immune Activation 5.6 Markers of Systemic Inflammation and Systemic ...
Denno, Donna M, Musser, Christine A, Nelson, Zakia C, Tarr, Phillip I, VanBuskirk, Kelley M   +4 more
core   +1 more source