Results 221 to 230 of about 857,467 (259)

ORMDL Proteins Turnover via Proteasome and Autophagy Is Cell‐Type Dependent and Tied to Ceramide Homeostasis

open access: yesThe FASEB Journal, Volume 40, Issue 6, 31 March 2026.
ORMDL proteins in the endoplasmic reticulum (ER) negatively regulate serine palmitoyltransferase (SPT) activity in response to the rate of de novo sphingolipid synthesis. Disruption of ceramide homeostasis by myriocin or fumonisin B1 (FB1) appears to destabilize the ORMDL‐SPT complex, leading to ORMDL degradation as a feedback mechanism.
Michal Mrkacek   +7 more
wiley   +1 more source

Exploring a gene co-expression network throughout the trypanosoma cruzi life cycle. [PDF]

open access: yesBMC Genomics
Inchausti L   +7 more
europepmc   +1 more source

Homogenization With Guaranteed Bounds via Primal‐Dual Physically Informed Neural Networks

open access: yesInternational Journal for Numerical Methods in Engineering, Volume 127, Issue 6, 30 March 2026.
ABSTRACT Physics‐informed neural networks (PINNs) have shown promise in solving partial differential equations (PDEs) relevant to multiscale modeling, but they often fail when applied to materials with discontinuous coefficients, such as media with piecewise constant properties. This paper introduces a dual formulation for the PINN framework to improve
Liya Gaynutdinova   +3 more
wiley   +1 more source

Planar and Pyramidal Pentacoordinate Selenium Atoms. [PDF]

open access: yesChemistry
Diego L   +3 more
europepmc   +1 more source

Increased default mode network activation in depression and social anxiety during upward social comparison. [PDF]

open access: yesSoc Cogn Affect Neurosci
Acuña A   +14 more
europepmc   +1 more source

Effect of Pefloxacin on <i>Clostridioides difficile</i> R20291 Persister Cells Formation. [PDF]

open access: yesAntibiotics (Basel)
Queraltó C   +9 more
europepmc   +1 more source

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