Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease driven by genetic and molecular disruptions affecting energy balance, protein homeostasis, and stress responses in nerve cells. Studies using human and rodent models identified convergent defects in mitochondria and synaptic function.
Federica Pilotto +11 more
wiley +1 more source
Prevalence and Predictors of Severity of Rebound Pain After Regional Anesthesia in Patients Undergoing Orthopedic Surgery: A Cross-Sectional Study. [PDF]
Gobezie NZ +10 more
europepmc +1 more source
AI‐Optimized Vanadium Oxide Multilayers for More Than 20‐fold Enhancement in Bolometric Performance
Machine‐learning‐optimized WxV1‐xOy multilayer thin films with graded doping achieve a high TCR (7.3 % K−1), reduced hysteresis, and low noise under CMOS‐compatible growth conditions. This approach overcomes the long‐standing trade‐off in microbolometers between linear response and performance, offering a universal bolometric parameter greatly enhanced
Jin‐Hyun Choi +8 more
wiley +1 more source
Linking Mitochondrial Gene Dysregulation to Immune Cell Shifts in Retinitis Pigmentosa. [PDF]
Liang J +14 more
europepmc +1 more source
HiST, a multiscale deep learning framework, reconstructs spatially resolved gene expression profiles directly from histological images. It accurately identifies tumor regions, captures intratumoral heterogeneity, and predicts patient prognosis and immunotherapy response.
Wei Li +8 more
wiley +1 more source
The Venom Proteome and Immunorecognition Profile of Clinically Important Echis carinatus sochureki from Northwestern India Underscores the Need for Regionally Specific Antivenoms. [PDF]
Kumar A +8 more
europepmc +1 more source
Integrated Biomimetic 2D-LC and Permeapad® Assay for Profiling the Transdermal Diffusion of Pharmaceutical Compounds. [PDF]
Neri I, Stevens C, Russo G, Grumetto L.
europepmc +1 more source
Muzyka żydowska na antenie Polskiego Radia w II RP – perspektywa galicyjska
Sylwia Jakubczyk-Ślęczka
openalex +2 more sources
Assessing measurement properties of EQ-5D-5L and ICECAP-A in patients with chronic depression in England. [PDF]
Assefa E +4 more
europepmc +1 more source

