Results 141 to 150 of about 14,297,124 (313)
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Boletín III, año 3, n. 19 bis, octubre 1994 [PDF]
, 1994 Revista mensual de la Universidad Carlos III de MadridEspecial de discursos del acto de apertura del curso 94/95Contiene: Discurso de Apertura del Curso Académico 1994/95, por el Magnifico y Excelenísimo Dr. D. Gregorio Peces-Barba Martínez, Rector de la
Universidad Carlos III de Madrid
core
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Carlos III, año 2, n. 10, septiembre 1997 [PDF]
, 1997 Revista mensual de la Universidad Carlos III de MadridContiene: Buenos días, Vicerrector; VIH/SIDA, una vida por delante; Y hablando de Israel, por ejemplo, un cuento; No sólo de pan; De perjuicios y ...
Universidad Carlos III de Madrid
core
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Carlos III, año 1, n. 5, octubre 1996 [PDF]
, 1996 Revista mensual de la Universidad Carlos III de MadridContiene: Manifiesto de El Escorial; "¿Qué fue de aquel equipo?"; Sobre los Euromasters; I Foro del Primer Empleo; I Festival Madrid Cultura ...
Universidad Carlos III de Madrid
core
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Metrology for III-V optosemiconductors: Dissertation
, 2017 Light-emitting diodes (LEDs) are III-V compound semiconductors manufactured by combining elements from group III (such as Al, Ga, and In) with elements from group V (such as N, P, As), forming compounds like GaN, GaInAs, and AlInP. High-power white LEDs are manufactured by coating a blue or an ultraviolet (UV) LED with phosphor, absorbing part of the ...
openaire +2 more sources
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source