Results 91 to 100 of about 165,778 (222)
Kidney Research and Clinical Practice, 2014 Background: The primary aim of the study was to investigate the cytokine/chemokine response in the kidney, lung, and liver following acute kidney injury (AKI). The secondary aim was to test whether α-melanocyte-stimulating hormone (α-MSH) could prevent a
Martin Skott +7 more
doaj +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Schematic representation of the spatiotemporal progression of the deleterious effects of early amyloidosis. Beginning as early as 1 h after i.c.v. injection of oligomeric Aβ1‐42, alterations in hippocampal function emerge, including aberrant oscillatory activity, deficits in synaptic plasticity and impairments in habituation ...
Souhail Djebari +7 more
wiley +1 more source
Atrial fibrosis in atrial fibrillation: Mechanisms, mapping techniques and clinical applications
The Journal of Physiology, EarlyView.Abstract figure legend Summary of key aspects of atrial fibrosis in atrial fibrillation, highlighting atrial fibrosis as a hallmark of atrial fibrillation (AF). (1) Different types of fibrosis (blue), illustrating reparative and reactive fibrosis; (2) fibrosis detection techniques (green), illustrating late gadolinium enhancement cardiac magnetic ...
Caterina Vidal Horrach +8 more
wiley +1 more source
Pathways of complement activation following intestinal ischemia-reperfusion in macaque [PDF]
Journal of Medical Biochemistry, 2012 Complement activation is a key component in the inflammation cascade. In the present study, intestinal ischemia-reperfusion (IIR) was introduced to macaques, and the pathways of complement activation in the multiple organ dysfunction syndrome (MODS ...
Lantao Xu, Yanyan Wu
doaj
Computational model of haemodynamics during atrial fibrillation
The Journal of Physiology, EarlyView.Abstract figure legend We developed a simplified computational model that replicates patient‐specific haemodynamics during both normal sinus rhythm and atrial fibrillation (AF). Our computational model comprises: (1) an electrical subsystem that generates unco‐ordinated atrial and irregular ventricular activation times characteristic of AF and (2) a ...
Felix Plappert +7 more
wiley +1 more source
Cortical responses to balance perturbations persist without active postural control
The Journal of Physiology, EarlyView.Abstract figure legend A robotic balance simulator was used to test whether cortical responses to balance perturbations are contingent on active balance control or instead reflect the detection of unexpected motion. Participants experienced identical support‐surface rotations (toes‐up and toes‐down) while actively controlling balance or while being ...
Daphne N. R. Jansen +3 more
wiley +1 more source
Journal of Advanced ResearchIntroduction: Prophylactic antifungal therapy has been widely used for critical patients, but it has failed to improve patient prognosis and has become a hot topic.
Yihui Chen +13 more
doaj +1 more source
Annals of Neurology, Volume 99, Issue 4, Page 863-870, April 2026.Objective Aneurysm wall enhancement (AWE) may predict aneurysm growth and rupture in the short‐term, but there is a lack of long‐term follow‐up studies. We aimed to determine whether unruptured intracranial aneurysms (UIAs) with AWE have a higher probability of aneurysm instability during long‐term follow‐up compared with those without AWE. Methods For
Laura T. van der Kamp +9 more
wiley +1 more source
Dual action of imeglimin on insulin secretion and sensitivity in type 2 diabetes
Diabetes, Obesity and Metabolism, Volume 28, Issue 4, Page 2744-2756, April 2026.Abstract Aims Imeglimin is a novel oral hypoglycemic agent approved for the treatment of type 2 diabetes in Japan, with dual actions to enhance insulin secretion and improve insulin sensitivity, suggested by preclinical evidence. However, the effect of imeglimin on tissue‐specific insulin sensitivity and glucose kinetics using glucose tracers is ...
Tsubasa Tajima +10 more
wiley +1 more source