Structural and Functional Siderophore Remodeling by Enzymatic Delipidation
A surprising functional switch in bacterial siderophores was discovered through genome mining and the analysis of environmental and pathogenic Pandoraea species. Pandorachelin B, a lipocyclopeptide that promotes swarming motility, is cleaved by a specialized acylase, yielding a ring‐contracted, homodetic cyclopeptide, pandorachelin A, which exhibits ...
Elena Herzog +5 more
wiley +2 more sources
A Hybrid Inverse Kinematics Framework for Biomimetic Redundancy Resolution in 7-DoF Humanoid Arms. [PDF]
Shi Y +5 more
europepmc +1 more source
Lymphatic Abnormalities in Noonan Syndrome Extend Beyond Clinically Apparent Disease
ABSTRACT Lymphatic disease represents a well‐described manifestation of Noonan syndrome (NS), yet the full phenotypic spectrum remains incompletely characterized, especially in asymptomatic individuals. We conducted a cross‐sectional study including 10 individuals with NS (four with peripheral lymphedema and six without) and 10 age‐ and sex‐matched ...
Inger Norlyk Sheyanth +7 more
wiley +1 more source
Environmental Identification of Novel Enzymes for Polyurethane and Polyamide Degradation
Heteroatom‐containing plastics such as polyurethanes and nylons are produced at scale yet remain largely unrecycled. Biocatalysts offer a promising route to depolymerization under mild conditions. Here, we present a screening platform for the discovery of novel polyurethane‐ and nylon‐degrading enzymes from environmental samples and demonstrate ...
Malthe Kjær Bendtsen +17 more
wiley +2 more sources
Optimized inverse kinematics solutions for a 6-DOF robot. [PDF]
Bayoume MO +3 more
europepmc +1 more source
Male Wistar rats were subjected to d‐galactose‐induced aging, with or without intermittent low‐dose intraperitoneal ozone administration, and evaluated over 8 weeks for redox status and physical performance, including physical health score, morbidity proportion, body weight, muscle strength, hair regrowth, and skin outcome.
Isabella Kurnia Liem +6 more
wiley +1 more source
Cross-cultural translation and content validity of the Determinants of Physical Activity Questionnaire (DPAQ) in a Dutch stroke rehabilitation population and their peers without stroke. [PDF]
Stokman-Meiland DCM +6 more
europepmc +1 more source
Monoallelic POLR3A Variants Cause Early‐Onset Peripheral Neuropathy
Objective Biallelic variants in genes encoding the RNA polymerase III complex (Pol III) cause a spectrum of neurological disorders primarily affecting the central nervous system. Monoallelic variants have been reported in the POLR3B subunit only, associated with neurodevelopmental disorder, epilepsy, and peripheral neuropathy.
Luiza L. P. Ramos +46 more
wiley +1 more source
[The Context-Sensitive Positive Health Questionnaire (CPHQ<sub>2.0</sub>), a broad health questionnaire based on a combination of the Capability Approach and the Positive Health concept]. [PDF]
Bloemen-van Gurp EJ +8 more
europepmc +1 more source
A new Patient‐Reported Outcome Scale to assess autoimmune Encephalitis: PROSE
Objective Autoimmune encephalitis (AIE) has long‐lasting effects. Generic clinical assessment‐scales insufficiently capture disease‐specific sequelae. Patient‐reported outcome measures (PROMs) assess outcomes important to patients, ensuring relevance in the clinic and trials.
Juliette Brenner +24 more
wiley +1 more source

