Results 61 to 70 of about 65,139 (240)

A Facile, Mechanochemical, Solvent-, and Catalyst-Free Synthesis of Functionalized 4-Thiazolidinones

open access: yesSynOpen, 2023
Simranpreet K. Wahan   +4 more
doaj   +1 more source

Çevik Dijital Dönüşümün Kilit Başarı Faktörleri: Çevik Bilgi Teknolojileri ve İnsan Kaynakları Uygulamalarının Normalleştirilmesi

open access: yesOnline Academic Journal of Information Technology
Değişimi rekabet avantajına çevirmeye odaklanan örgüte özgü çevik uygulamalarda yalından yararlanılmaktadır. Bu çalışma, çevik dijital dönüşüm başarısının temelinde olan çevik bilgi teknolojileri (BT) ve insan kaynakları (İK) uygulanmalarına yönelik ...
Fatma Zehra Köker
doaj   +1 more source

Deep Learning Prediction of O‐Glycopeptide Tandem Mass Spectra Enhances O‐Glycoproteomics

open access: yesAdvanced Science, EarlyView.
DeepGPO integrates Transformer and graph neural networks with tailored training strategies, including data augmentation, loss re‐weighting, and pre‐training, to achieve high‐quality O‐glycopeptide MS/MS spectra prediction. The predicted MS/MS spectra are used to localize O‐glycosylation sites from HCD MS/MS data, enhancing O‐glycoproteomics analysis ...
Yu Zong, Yuxin Wang, Liang Qiao
wiley   +1 more source

Human Foetal Neuroblasts Exhibit BK Channel‐Dependent Membrane Voltage Oscillations upon Depolarization

open access: yesAdvanced Science, EarlyView.
Primary cultures of neuroblasts isolated from the nucleus basalis of Meynert of 12‐weeks‐old human foetuses were prepared. Whole‐cell patch‐clamp recordings were performed by injecting a depolarizing stimulus current (+500 pA; 500 ms), and the membrane voltage recorded; this stimulus current evoked periodic‐like oscillations in membrane voltage ...
Elisabetta Coppi   +9 more
wiley   +1 more source

Metasurface‐Enabled Helical Wavefront Fingerprint Metrology for Quantitative Retrieval of Liquid Optical Constants

open access: yesAdvanced Science, EarlyView.
A metasurface‐enabled helical wavefront fingerprint (MHWF) paradigm is proposed for quantitative and specific retrieval of a liquid medium's refractive index and extinction coefficient. The liquid's complex dielectric response governs the wavefront evolution of the metasurface‐generated focused vortex beam, forming a distinctive three‐dimensional ...
Yuting Zhou   +10 more
wiley   +1 more source

A névegységesítés eredményei a magyar tengerfenék-domborzati nevek körében [Hungarian results of the standardization of undersea feature names]

open access: yesNévtani Értesítő, 2014
The author of the present paper, a cartographer, has studied all sorts of questions in relation to geographical names for the correct representation of seas.
Márton, Mátyás
doaj  

CHANGING APPROACHES TO INDIGENOUS KNOWLEDGE AND ITS RELATIONSHIP WITH SCIENTIFIC KNOWLEDGE

open access: yesHumaniora, 2016
Prevailing views on indigenous knowledge (IK) rely on a binary contrast between indigenous knowledge and scientific knowledge (SK), where the former is either dismissed as backward or judged superior in terms of its sustainability.
Ngo Thi Puong Lan
doaj   +1 more source

Nucleoside‐Modified mRNA Encoding Alpha‐Galactosidase A Ameliorates Fabry Disease Phenotypes in Human IPSC‐Derived Cardiomyocytes

open access: yesAdvanced Science, EarlyView.
Human iPSC‐derived Fabry cardiomyocytes exhibited broad transcriptional dysregulation, apoptosis, mitochondrial dysfunction, impaired reactive oxygen species handling, altered contractility, and abnormal calcium transient decay, potentially mediated by phospholamban hyperphosphorylation.
Malte Juchem   +24 more
wiley   +1 more source

Targeting the Small- and Intermediate-Conductance Ca2+-Activated Potassium Channels: The Drug-Binding Pocket at the Channel/Calmodulin Interface

open access: yesNeurosignals, 2014
The small- and intermediate-conductance Ca2+-activated potassium (SK/IK) channels play important roles in the regulation of excitable cells in both the central nervous and cardiovascular systems.
Meng Cui   +4 more
doaj   +1 more source

Ik zie ik zie wat ik niet zag

open access: yes, 2018
Mensen die te kampen hebben met een beperking kunnen op veel onbegrip stuiten op het moment dat zij proberen deel te nemen aan de samenleving. Dat geldt vooral voor hen van wie de beperking niet (onmiddellijk) duidelijk zichtbaar of merkbaar is. In dit onderzoek wordt een e-learningsmodule, ontworpen om medewerkers van de Gemeente Amsterdam beter ...
van Zal, Stefanie, Kwekkeboom, Rick
openaire   +1 more source

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