Results 121 to 130 of about 63,533 (294)

Analysis of C4 Concentrations to Predict Impact of Patient‐Reported Diarrhea Associated With the Ileal Bile Acid Transporter Inhibitor Linerixibat

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 596-605, March 2025.
ABSTRACT Linerixibat, an ileal bile acid transporter (IBAT) inhibitor, is being evaluated for the treatment of pruritus in primary biliary cholangitis (PBC). Diarrhea is commonly reported with this drug class as IBAT inhibition redirects bile acids (BA) to the colon.
Fernando Carreño, Rashmi Mehta, Andrea Ribeiro de Souza, Jon Collins, Brandon Swift   +4 more
wiley   +1 more source

Enteric diseases in pigs from weaning to slaughter [PDF]

, 2003
The general aim of this thesis was to study enteric diseases in growing pigs, with special reference to diseases caused by Brachyspira hyodysenteriae and Lawsonia intracellularis. The occurrence of enteric diseases in “growers” is a problem of increasing
Jacobson, Magdalena
core  

Bile acid metabolism and sleep: Mechanistic interplay and clinical implications of the gut–liver–brain axis

Sleep Research, EarlyView.
Abstract The bidirectional interplay between sleep and metabolic homeostasis is fundamental to physiological health. While the roles of glucose and lipid metabolism in sleep regulation have been extensively characterized, bile acids (BAs), which are traditionally viewed as digestive surfactants, are emerging as critical metabolic messengers with ...
Yu Jiang, Shuangyan Li, Dhirendra Paudel, Miaoqin Tan, Bin Zhang   +4 more
wiley   +1 more source

Guidelines for Essential Trauma Care: Second Edition (2026)

World Journal of Surgery, EarlyView.
Injury is a major cause of death and disability globally, with the highest burden in low‐ and middle‐income countries (LMICs). Strengthening the organization and planning for trauma care (care of the injured) can improve care and lower mortality. In 2004, the International Association for Trauma Surgery and Intensive Care (IATSIC) and the World Health ...
Charles Mock, Timothy C. Hardcastle, Christine Gaarder, Amit Gupta, Adam Gyedu, Manjul Joshipura, Elmin Steyn, on behalf of the Essential Trauma Care revision author group, Valencia Adjei, Roger Alcock, Vanda Amado, Michael Boampong, Sanjeev Booi, Petra Brysiewicz, Corazon Cabanilla‐Manuntag, Cristiane de Alencar Domingues, Ghada Elhadari, Ranjith Nanda Ellawala, Sarnai Erdene, Ama Akoma Essuman, Jorge Esteban Foianini, Filippo Gatti, Armando Garcia Guererra, Greg Hynes, Adil Haider, Sandy Ingless, Balavenkata Jagannathan, Helen Jowett, Knut Magne Kolstadbråten, Sonja Krofak, Aireen Patricia Madrid, Tina Tomić Mahečić, Claude Martin, Daniel Ntogwrachu, Bisola Onajin‐Obembe, Nhobojit Roy, Andres Rubiano, Niisoja Mensah Torto, Ben Wachira, Meg Walmsley, Torben Wisborg, Elma Wong   +41 more
wiley   +1 more source

Paediatric renal transplantation: Paediatric surgeons' perspective

Surgical Practice, EarlyView.
Abstract Renal transplantation is the most effective treatment for paediatric end‐stage renal disease (ESRD), offering advantages in survival, growth and neurocognitive development that surpass other renal replacement therapies (RRT). The paediatric setting, however, introduces distinct complexities that distinguish it from adult practice.
Adrian Chi‐heng Fung, Mary Kim Elizabeth Tan Cudia, Ivy Hau‐yee Chan, Kenneth Kak‐yuen Wong   +3 more
wiley   +1 more source

Practice Patterns and Outcomes of Preoperative Mechanical Bowel Preparation and Oral Antibiotics for Restorative Elective Colorectal Surgery: Nationwide Analysis of the ACS‐NSQIP Australian Data

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background There is increasing evidence that the addition of preoperative antibiotics (OAB) reduces infectious complications after colorectal surgery. To understand practice patterns in Australia, Australian hospitals participating in the American College of Surgeons National Surgical Quality Improvement Program (ACS‐NSQIP) collecting targeted
Joseph Do Woong Choi, Nguyen Huynh, Kalai Kuppusamy, David Clark, Richard Bryant, Aleksandra Edmundson, Rebecca Radford, Andrew Gilmore, Yasser Farooque, Elaine Zhang, Nimmi Kumar, Matthew Morgan, Neil Merrett, Mingjuan Zeng, Bruce Hodge, Andrew Sutherland, Jimmy Chin Li Lee, Andrea Giles, Diana Tam, Emma Plecas, Boris Strekozov, Chantel Gablonski, Shella de Robles, Jennifer Hearn, Gregory Nolan, Michelle Cooper, Rebecca Boyle, Kelvin Kwok, Ian Incoll, Caitlin Queripel, Amy Cao, Nimalan Pathma‐Nathan, Toufic El‐Khoury, Arthur J. Richardson, Kerry Hitos, James Wei Tatt Toh   +35 more
wiley   +1 more source

Dynamic changes of urinary microbiota in patients with bladder cancer after surgery and its clinical significance

Frontiers in Immunology
Bladder cancer is one of the most common malignancies of the urogenital system, with a high incidence and mortality. The treatment of bladder cancer is diverse, with surgical treatment being the most common approach, including transurethral resection of ...
Ye Lang, Pei Li, Ruixiang He, Bo Zhu, Guang Wang, Jiongming Li   +5 more
doaj   +1 more source

Appendiceal Crohn's Disease Manifesting as Appendiceal Malignancy: A Case Report and Review of the Literature

The Kaohsiung Journal of Medical Sciences, EarlyView.
Ming‐Jung Meng, Tai‐Di Chen, Puo‐Hsien Le, Chia‐Jung Kuo   +3 more
wiley   +1 more source

One‐Year Effectiveness of Upadacitinib in Perianal Crohn's Disease: A Real‐World GETAID Study

Alimentary Pharmacology &Therapeutics, EarlyView.
In a real‐world cohort of patients with highly refractory perianal Crohn's disease, upadacitinib induced clinical remission at 12 months in 26% of patients with fistulizing disease and 25% of those with isolated anal ulcerations. ABSTRACT Introduction Upadacitinib (UPA) is effective for treating luminal Crohn's disease (CD), but data on perianal CD ...
Nicolas Richard, Philippe Seksik, Romain Altwegg, Maria Nachury, David Laharie, Stéphane Nancey, Benoît Coffin, Anne‐Laure Pelletier, Mathieu Uzzan, Aurélien Amiot, Morgane Amil, Lucine Vuitton, Mathurin Fumery, Anne Bozon   +13 more
wiley   +1 more source

Laparoscopic Modified One Anastomosis Gastric Bypass for Severe Obesity After Pancreaticoduodenectomy: A Safe Approach to the Hostile Abdomen, a First Case Report

The Kaohsiung Journal of Medical Sciences, EarlyView.
Chih‐Kun Huang, Ming‐Che Hsin, Long‐Bin Jeng, Ting‐Wei Chang   +3 more
wiley   +1 more source