Results 151 to 160 of about 63,533 (294)

Loss of VMP1 Impairs Tight Junction Recycling and Aggravates Intestinal Barrier Dysfunction in Inflammatory Bowel Disease

Advanced Science, Volume 13, Issue 25, 4 May 2026.
This study identifies vacuole membrane protein 1 (VMP1) as a critical regulator of intestinal epithelial barrier homeostasis. VMP1 facilitates the recruitment of CORO1C to late endosomes, supporting Retromer‐mediated recycling of the tight junction protein Occludin.
Jiawei Zhao, Jianjun Zou, Chen Zhou, Yingui Wang, Yiman Liu, Yanqing Zhou, Yuxiang Wang, Xinyu Zhang, Huishu Yang, Hongjie Yin, Dongsheng Bai, Yue Zhao, Na Lu   +12 more
wiley   +1 more source

Glucuronolactone Promotes Mucin Sulfation to Alleviate Deoxynivalenol‐Induced Intestinal Injury via Microbiota‐Dependent and ‐Independent AHR Activation

Advanced Science, Volume 13, Issue 25, 4 May 2026.
Glucuronolactone (GLU) as a natural metabolite of glucose, increases Lactobacillus amylovorus abundance and luminal IAA level to activate AHR signaling. In addition, GLU itself can directly elevate AHR signaling activity independently of microbiota and IAA.
Chenbin Cui, Beibei Zhang, Jiaxi Tang, Jing Hou, Yueqin Qiu, Kaiguo Gao, Li Wang, Zongyong Jiang, Xuefen Yang   +8 more
wiley   +1 more source

Ileal Neuroendocrine Neoplasm: Diagnostic Imaging, Risk Factors, and Management Implications

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Early detection of small bowel neuroendocrine tumors (NETs), even when incidentally discovered, is crucial for improving outcomes. This case highlights the importance of recognizing incidental findings during imaging, as timely surgical intervention and multidisciplinary management can prevent progression, mitigate morbidity, and improve ...
Mahfujul Z. Haque, Abdulmalik Saleem, Ammad Chaudhary, Taher Jamali, Kimberly Tosch   +4 more
wiley   +1 more source

Natural Products as the Modulators of Gut Microbiota: A Pool for the Development of New Treatment Against Obesity?

Food Frontiers, Volume 7, Issue 3, May 2026.
Natural compounds regulate gut microbiota by improving microbial balance and increasing probiotics, which boost short‐chain fatty acid production to alleviate insulin resistance and inflammation. Additionally, they stimulate appetite‐suppressing hormones through bile acid signaling, while inhibiting pathogenic bacteria to repair intestinal barrier ...
Hongchao Yuan, Yau‐Yuen Chan, Guang Chen, Lin Xu, Cheng Zhang, Guoyi Tang, Yibin Feng, Ning Wang   +7 more
wiley   +1 more source

Reply to: On the Clinical Utility of Hybrid Endoscopy in Crohn's Disease

DEN Open, Volume 7, Issue 1, April 2027.
Takahiro Ito
wiley   +1 more source

Inactivation Strategies of Clostridium perfringens in Foods: Current Challenges and Emerging Interventions

Food Frontiers, Volume 7, Issue 3, May 2026.
Clostridium perfringens forms heat‐resistant spores that complicate food safety. Physical methods (thermal processing, HPP, vacuum cooling, ozone treatments) and chemical interventions (natural antimicrobials, phosphates, nitrate/nitrite, organic acids) reduce vegetative cells and spores, though spore resistance remains a major challenge in food and ...
Deepak Subedi, Bharath Mallavarapu, Pranita Patil, Sujitha Bhumanapalli, Sandesh Chapagain, Kham Bahadur Khatri, Milan Kandel, Amit Kumar Singh   +7 more
wiley   +1 more source

Short Ileal Microvillus Length Phenotype Associates with Progression from Inflammatory to Complicated Disease Behavior in Pediatric Crohn's Disease. [PDF]

Inflamm Bowel Dis
Haberman Y, Braun T, Karns R, Bartel CA, Bonkowski E, Simpson KF, Walters TD, Hyams JS, Liu TC, Kugathasan S, Denson LA, VanDussen KL.   +11 more
europepmc   +1 more source

Magnolol Improves Intestinal Antioxidant Capacity and Barrier Function by Activating the Nrf2 Signaling Pathway in a Piglet Model

Food Frontiers, Volume 7, Issue 3, May 2026.
ABSTRACT Magnolol is a natural bioactive phenolic compound with potent antioxidant properties and plays an important role in modulating intestinal healthy. However, the underlying mechanisms of magnolol in alleviating intestinal oxidative stress damage and improving the intestinal barrier integrity remain unknown. Thus, this study aimed to evaluate the
Mengyao Fang, Kang Yang, Yiyan Cui, Ting Rong, Dun Deng, Pan Yang, Zhimei Tian, Min Song, Xianyong Ma, Miao Yu   +9 more
wiley   +1 more source

Adult ileocolic intussusception due to a terminal ileal lipoma mimicking malignancy: a rare case report. [PDF]

Ann Med Surg (Lond)
Abduh MS, Rezk YS, Abdelkhalek EM, Shehata MS, Aldaqal SM.   +4 more
europepmc   +1 more source

LL‐37: Biological Mechanisms and Emerging Therapeutic Applications in Intestinal Disease

Immunity, Inflammation and Disease, Volume 14, Issue 5, May 2026.
ABSTRACT Human cathelicidin peptide LL‐37 is encoded by the CAMP gene and plays a key role in innate immunity. It maintains intestinal homeostasis through antibacterial, immunomodulation, and tissue repair functions. This paper reviews the multiple functions of LL‐37 in the intestinal‐immune axis and its contribution to intestinal immune homeostasis. A
Qichao Liu, Peng Xu, Cheng Zhang
wiley   +1 more source