Results 271 to 280 of about 203,883 (351)

The High‐Altitude Adaptation Characteristics of Microbiota‐Host Cross‐Talk in Yak Gastrointestinal Track

open access: yesAdvanced Science, Volume 13, Issue 1, 5 January 2026.
In this study, a single‐cell atlas of 117,019 yak gastrointestinal cells across 54 subtypes identified HNF4A and SREBF2 as key transcription factors targeting MYO6 gene. Cross‐species and multi‐omics analyses reveals epithelial cells as key regulators that, through interactions with microbes, particularly Bacillus, facilitate flexible energy supply and
Chun Huang   +12 more
wiley   +1 more source

Ileal bile acid transporter inhibitors in Alagille syndrome and Progressive Familial Intrahepatic Cholestasis: A systematic review into dose–response

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 1, Page 119-135, January 2026.
Ileal bile acid transporter inhibitors (IBATi), including maralixibat and odevixibat, are a novel approach to the treatment of paediatric cholestatic liver diseases, such as Alagille syndrome (ALGS) and different forms of progressive familial intrahepatic cholestasis (PFIC).
Alise D. E. de Groot   +5 more
wiley   +1 more source

Molecular Deconvolution of Circulating “Other Cells”: A Reliable Predictive Marker of Therapy Response and Survival in Neuroendocrine Tumor Patients Receiving 177Lu‐DOTATATE PRRT

open access: yesCancer Medicine, Volume 15, Issue 1, January 2026.
ABSTRACT Purpose To assess the prognostic impact of pre‐treatment circulating other cells on treatment response and survival in neuroendocrine tumor (NET) patients receiving Peptide Receptor Radionuclide Therapy (PRRT) with 177Lu‐DOTATATE. Methods Healthy donors (HDs, n = 81) and NET patients (n = 137) were analyzed.
Mahesh K. Padwal   +3 more
wiley   +1 more source

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