Results 271 to 280 of about 199,284 (357)

Changes in gastrointestinal motility and gut hormone secretion after Roux‐en‐Y gastric bypass and sleeve gastrectomy for individuals with severe obesity

open access: yesClinical Obesity, Volume 15, Issue 2, April 2025.
Summary Background Bariatric surgery is very effective in long‐term weight management. The present study was undertaken to investigate the short‐term effects of sleeve gastrectomy (SG) and of Roux‐en‐Y gastric bypass (RYGB) on (a) gastrointestinal (GI) motility, that is gastric emptying and oro‐cecal transit time and (b) secretion of regulatory gut ...
Jennifer A. Wilbrink   +4 more
wiley   +1 more source

Integrative proteomic analysis provides novel therapeutic insights for etiological subtypes of diabetes

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Type 2 diabetes (T2D) is a highly heterogeneous disease characterised by subtypes with variations in aetiology, disease progression, and risk of complications. However, potential drug targets for these subtypes have not been explored. This study aims to investigate potential drug targets by integrating proteomics.
Jiahe Wei   +8 more
wiley   +1 more source

Coated glucose microbeads stimulate enteric hormone release and improve glucose tolerance in Phase 1 and 2 clinical trials

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Incretin agonists are used to treat obesity and metabolic dysfunction. Instead of systemically delivering high levels of hormone receptor agonists that can lead to adverse effects, we tested and optimized oral microbead formulations that activate endogenous enteroendocrine signalling systems via distal nutrient‐sensing cells.
Kai Deusch   +9 more
wiley   +1 more source

Transcriptomic and proteomic profiling reveal immune and metabolic dysregulation in the colonic mucosa of people living with HIV with incomplete immune recovery. [PDF]

open access: yesFront Immunol
Kaarbø M   +12 more
europepmc   +1 more source

The proteomic differences and expression of fatty acid‐binding protein 6 (FABP6) associated with gastrointestinal injury in horses with oral administration of a clinical dose of phenylbutazone

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Phenylbutazone (PBZ) can potentially induce gastrointestinal ulceration, and early detection of PBZ‐induced gastroenteropathy will be useful for the diagnosis, treatment, and prevention of PBZ toxicity. Objectives To identify putative proteins associated with equine gastric ulcer syndrome after clinical dose (4.4 mg/kg ...
Ruethaiwan Vinijkumthorn   +6 more
wiley   +1 more source

Endoscopic assessment of terminal ileum in screening colonoscopy: is it worth the effort? [PDF]

open access: yesClin Endosc
Dąbkowski K   +7 more
europepmc   +1 more source

Control of post-transplant lymphoproliferative disorders and Kaposi's sarcoma by modulation of immunosuppression [PDF]

open access: yes, 1987
Breinig, MK   +10 more
core  

Risk factors for strangulating lipoma obstruction and lipomata in horses

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Strangulating lipoma obstruction (SLO) is the most common cause of equine small intestinal strangulation and is fatal without surgery. Currently, epidemiological information is primarily limited to signalment‐related risk factors and requires further investigation.
Alex Gillen   +11 more
wiley   +1 more source

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