Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro +6 more
wiley +1 more source
Yerel yönetim bankacılığı: İller bankasının değişim süreci üzerine bir inceleme [PDF]
Cumhuriyetin kurulmasından sonra, savaşlarda harap olmuş ülkemizin yerel yönetimler alanında gereksinim duyulan finansmanını ve eş güdümünü sağlamak üzere 1933 yılında Belediyeler Bankası kurulmuştur.
Ahmet Avşar Şimşek
core
Assessing the treatment effects in apraxia of speech: introduction and evaluation of the Modified Diadochokinesis Test [PDF]
Background: The number of reliable and valid instruments to measure the effects of therapy in apraxia of speech (AoS) is limited. Aims: To evaluate the newly developed Modified Diadochokinesis Test (MDT), which is a task to assess the effects of rate and
Reinders-Messelink, Heleen A. +16 more
core +1 more source
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller +14 more
wiley +1 more source
Belediyelerin finansman ihtiyacının karşılanmasında İller Bankası’nın rolü ve yeniden yapılandırılması [PDF]
Halka en yakın yönetim birimleri olarak belediyelerin günümüzdeki önemi artmakta, belediyelere çeşitli ve her gün yenisi eklenen sorumluluklar yüklenmekte, bu artan harcama sorumluluklarıyla doğru orantılı olarak da belediyelerin finansman ihtiyacının ...
Yaş, Hakan
core
A 17 Year Old With Developmental Delay Presenting With Increasing Confusion and Imbalance
ABSTRACT Methylmalonic acidemia is an autosomal recessive genetic disorder primarily caused by defects in methylmalonyl‐CoA mutase and cobalamin (vitamin B12) metabolism. These defects disrupt the tricarboxylic acid cycle and oxidative phosphorylation, leading to the abnormal accumulation of metabolic products such as methylmalonic acid, propionic acid,
Wei Zhao, Yingli Zhang, Hongliang Zheng
wiley +1 more source
Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito +8 more
wiley +1 more source
Türkiye Ekonomisinde Büyümenin Sektörel Belirleyicileri: İller Düzeyinde 2004-2014 Yılları Arasında Ampirik Bir İnceleme [PDF]
Türkiye ekonomisinde iller düzeyinde büyümenin sektörel belirleyicileri, bu çalışmada statik ve dinamik panel veri analizi vasıtasıyla 2004-2015 yılları arasında araştırılmaktadır.
Doruk, Ömer Tuğsal
core
Intraoperative monitoring of cerebrovascular autoregulation in infants and toddlers receiving major elective surgery to determine the individually optimal blood pressure - a pilot study. [PDF]
Iller M +10 more
europepmc +1 more source
ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro +14 more
wiley +1 more source

