Predictors of fatigue severity in early systemic sclerosis: a prospective longitudinal study of the GENISOS cohort. [PDF]
ObjectivesLongitudinal studies examining the baseline predictors of fatigue in SSc have not been reported. Our objectives were to examine the course of fatigue severity over time and to identify baseline clinical, demographic, and psychosocial predictors
Assassi, Shervin+10 more
core +10 more sources
SARS-CoV-2 neutralizing antibodies in patients with varying severity of acute COVID-19 illness [PDF]
In order to support vaccine development, and to aid convalescent plasma therapy, it would be important to understand the kinetics, timing and persistence of SARS-CoV-2 neutralizing antibodies (NAbs), and their association with clinical disease severity ...
Gomes, Laksiri+12 more
core +2 more sources
The relationship among the health-related quality of life, illness severity, personality and psychiatric symptoms in patients with psoriasis: an empirical investigation [PDF]
Background: Psoriasis is a complex and chronic inflammatory skin disorder. The mechanisms underlying this immune-mediated disease are not clear, but some evidence indicates that specific personality features and symptom patterns may play an important ...
Annalisa Tanzilli+7 more
core +1 more source
Sepsis biomarkers in unselected patients on admission to intensive or high-dependency care [PDF]
Although many sepsis biomarkers have shown promise in selected patient groups, only C-reactive protein and procalcitonin (PCT) have entered clinical practice.
Berger, Mario+10 more
core +2 more sources
Solving Severely Ill-Posed Linear Systems with Time Discretization Based Iterative Regularization Methods [PDF]
Recently, inverse problems have attracted more and more attention in computational mathematics and become increasingly important in engineering applications. After the discretization, many of inverse problems are reduced to linear systems. Due to the typical ill-posedness of inverse problems, the reduced linear systems are often ill-posed, especially ...
arxiv +1 more source
A scale for assessing the severity of diseases and adverse drug reactions: Application to drug benefit and risk [PDF]
Physicians were interviewed to assess their willingness to risk adverse drug reactions among patients. These untoward reactions were ranked according to severity and weighted against the primary illness being treated. A specially designed questionnaire
Eiben, Carl+2 more
core +2 more sources
The influence of 'significant others' on persistent back pain and work participation: a qualitative exploration of illness perceptions [PDF]
Background Individual illness perceptions have been highlighted as important influences on clinical outcomes for back pain. However, the illness perceptions of 'significant others' (spouse/partner/close family member) are rarely explored, particularly ...
A Cano+45 more
core +2 more sources
Sexual Dysfunction in People with Multiple Sclerosis: The Role of Disease Severity, Illness Perception, and Depression [PDF]
Despite being a common issue in people with multiple sclerosis (pwMS), sexual dysfunction is still underinvestigated. This work aims to assess the potential determinants of sexual dysfunction in pwMS by considering its relationship with disease severity (
Abbadessa Gianmarco+26 more
core +1 more source
Infant Illness Severity and Perinatal Post-traumatic Stress Disorder after Discharge from the Neonatal Intensive Care Unit [PDF]
Background Risk factors for perinatal posttraumatic stress disorder (PTSD) among parents of an infant in the NICU have varied in previous literature. The relationships between perception of illness severity and objective measures of illness severity with
Johnson, Teresa S.+5 more
core +1 more source
Measurement of resident workload in paediatric intensive care [PDF]
OBJECTIVE: To measure the workload of residents in a paediatric intensive care unit (PICU) and to compare this value with the possible explanatory variables "nine equivalents of nursing manpower use score" (NEMS), length of stay (LOS), patient age and ...
Cannizzaro, Vincenzo+3 more
core +1 more source