Results 221 to 230 of about 934,633 (333)

Increasing illness severity is associated with global myocardial dysfunction in the first 24 hours of sepsis admission. [PDF]

Ultrasound J, 2022
Ehrman RR, Bredell BX, Harrison NE, Favot MJ, Haber BD, Welch RD, Levy PD, Sherwin RL.   +7 more
europepmc   +1 more source

Gut Bacteria Improve Depressive Symptoms by Degrading Cortisol into Androgen

Advanced Science, EarlyView.
Chronic stress is an important risk factor for stress‐related disorders such as depression. Stress hormone cortisol is essential for the pathogenesis of stress‐related disorders such as depression. Some gut microbiota degraded cortisol, and improve depressive symptoms.
Xiong Wang, Qing Wu, Hao‐Long Zeng, Yin Shen, Hong‐Han Zhang, Jun Gong, Qi Zhang, Jia‐Zhao Xie, Da‐Wei Ye, Zi‐Yong Sun, Zhong‐Chun Liu, Li‐Ming Cheng, Di Li   +12 more
wiley   +1 more source

Association Between Nurse Copatient Illness Severity and Mortality in the ICU. [PDF]

Crit Care Med
Riman KA, Davis BS, Seaman JB, Kahn JM.
europepmc   +1 more source

The value of comorbidities and illness severity scores as prognostic tools for early outcome estimation in patients with aneurysmal subarachnoid hemorrhage. [PDF]

Neurosurg Rev, 2022
Malinova V, Sheri T, Kranawetter B, Moerer O, Rohde V, Mielke D.   +5 more
europepmc   +1 more source

Winning hearts and minds: the impact of illness severity and pre-morbid mental health on wellbeing after acute myocardial infarction with cardiogenic shock [PDF]

Walter Schiffer, Nancy K. Sweitzer, Christian Jung   +2 more
openalex   +1 more source

Influence of severity of illness on the effects of eritoran tetrasodium (E5564), a TLR4 antagonist, in patients with severe sepsis [PDF]

, 2009
S M Opal, AC Kalil, SP LaRosa, Jagadish Gogate, Melvyn Lynn, AE Wittek, the Eritoran Sepsis Study Group   +6 more
openalex   +1 more source

Taurocholic Acid Is Associated With Disturbed Functional Connectivity in the Hippocampus of Patients With Depression

Advanced Science, EarlyView.
This study identifies elevated taurocholic acid (TCA) in Major Depressive Disorder patients. Gut microbiome‐associated TCA impairs hippocampal neurogenesis, triggers microglia activation, and elicits depression‐like behavior in mice via the S1PR2. In patients, functional neuroimaging reveals that serum TCA levels correlate with altered functional ...
Xiaoying Cai, Taipeng Sun, Mengzhen Feng, Gang Chen, Junchi Zhou, Hong Zhuang, Dan Wang, Ying Chen, Zhen Cheng, Zhi Xu, Xiao Zheng, Xueli Zhang, Yonggui Yuan   +12 more
wiley   +1 more source

Predictive Ability of an Illness Severity Measure: Implications for Nursing Research. [PDF]

J Nurs Meas, 2021
Lindley LC, Fortney CA, Cozad MJ.
europepmc   +1 more source

Astrocytic PERK Deficiency Drives Prefrontal Circuit Dysfunction and Depressive‐Like Behaviors

Advanced Science, EarlyView.
Chen et al. show that the endoplasmic reticulum (ER) stress sensor PERK is downregulated in prefrontal cortex (PFC) astrocytes in major depressive disorder and in chronic‐stress mouse models. In young mice, astrocyte‐specific PERK loss reduces the synaptogenic cue thrombospondin‐1 (TSP1), leading to synaptic and circuit deficits and depressive‐like ...
Kai Chen, Riya Gupta, Yosuke M. Morizawa, Yu Qin, Xingyu Du, Cynthia Pang, Osama Al‐Dalahmah, Maura B. Dupont, Guang Yang   +8 more
wiley   +1 more source

A simple electronic medical record-based predictors of illness severity in sepsis (sepsis) score. [PDF]

PLoS One
Cressman AM, Wen B, Saha S, Jun HY, Waters R, Lail S, Jabeen A, Koppula R, Lapointe-Shaw L, Sheehan KA, Weinerman A, Daneman N, Verma AA, Razak F, MacFadden D.   +14 more
europepmc   +1 more source