Results 71 to 80 of about 934,633 (333)

Explaining adherence to self-care behaviours amongst adolescents with food allergy: a comparison of the health belief model and the common sense self-regulation model [PDF]

, 2014
OBJECTIVES: To identify explanations for adherence to self-care behaviours amongst adolescents with food allergy-induced anaphylaxis using two social cognition models: the health belief model (HBM) and the common sense self-regulation model (CS-SRM).
Aiken, Ajzen, Bock, Bock, Box, Carpenter, Champion, DiMatteo, Gallagher, Gillibrand, Goldberg, Hagger, Henshaw, Kim, Knibb, Leventhal, Macadam, Meyer, Moss-Morris, Ogden, Pereira, Pumphrey, Pumphrey, Resuscitation Council (UK), Richards, Rogers, Rosenstock, Sampson, Sampson, Sutton, Sutton, Velde   +31 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Comparison of Serum Vitamin D Status in Critically ill and Non-critically ill Children and its Relationship with Illness Severity and Clinical Outcomes: A Case–Control Study

International Journal of Medicine and Health Development
Background: The role of vitamin D in immune function is well-established in adults, but remains unclear in children. Objectives: We aimed to determine the prevalence of vitamin D deficiency in critically ill versus non-critically ill children and the ...
Eziamaka J. Enemuo, Herbert A. Obu, Ifeyinwa D. Nnakenyi   +2 more
doaj   +1 more source

A latent class analysis of parental bipolar disorder: examining associations with offspring psychopathology [PDF]

, 2015
Bipolar disorder (BD) is highly heterogeneous, and course variations are associated with patient outcomes. This diagnostic complexity challenges identification of patients in greatest need of intervention.
Freed, Rachel D., Henin, Aude, Nierenberg, Andrew A., Otto, Michael W., Tompson, Martha C.   +4 more
core   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Correlates of Illness Severity in Infectious Mononucleosis

Canadian Journal of Infectious Diseases and Medical Microbiology, 2014
INTRODUCTION: Understanding the spectrum and frequencies of Epstein-Barr virus (EBV) complications and markers of illness severity in immunocompetent patients with primary EBV infection will inform management of patients with EBV-related illnesses.
John Odame, Joan Robinson, Nasser Khodai-Booran, Simon Yeung, Tony Mazzulli, Derek Stephens, Upton D Allen   +6 more
doaj   +1 more source

A proposed severity classification of borderline symptoms using the borderline symptom list (BSL-23)

Borderline Personality Disorder and Emotion Dysregulation, 2020
Background The Borderline Symptom List (BSL-23) is a well-established self-rating instrument to assess the severity of borderline typical psychopathology. However, a classification of severity levels for the BSL-23 is missing.
Nikolaus Kleindienst, Martin Jungkunz, Martin Bohus   +2 more
doaj   +1 more source

Disparity between General Symptom Relief and Remission Criteria in the Positive and Negative Syndrome Scale (PANSS): A Post-treatment Bifactor Item Response Theory Model. [PDF]

, 2017
Objective: Total scale scores derived by summing ratings from the 30-item PANSS are commonly used in clinical trial research to measure overall symptom severity, and percentage reductions in the total scores are sometimes used to document the efficacy of
Anderson, Ariana E, Bilder, Robert M, Han, Carol, Mansolf, Maxwell, Marder, Stephen R, Reise, Steven P   +5 more
core  

Factors Associated with Severe Disease from Malaria, Pneumonia and Diarrhea among Children in Rural Tanzania - a Hospital-Based Cross-Sectional Study. [PDF]

, 2012
Mild cases of malaria, pneumonia and diarrhea are readily treatable with complete recovery and with inexpensive and widely available first-line drugs. However, treatment is complicated and expensive, and mortality is higher when children present to the ...
Hinderaker, Sven Gudmund, Kahabuka, Catherine, Kvåle, Gunnar   +2 more
core   +2 more sources

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source