Results 171 to 180 of about 531,444 (314)

P698: Accurate genotyping of high homology HBA and SMN genes from whole exome sequencing

Genetics in Medicine Open
Ashley Carroll, Jon Albay, Dianne Hernandez, Jonathan Nery, Susanne Angelow, Aaron Halpern, Kingshuk Mukherjee, Eric Roller, Vitor Onuchic, James Han   +9 more
doaj   +1 more source

Comparative Evaluation of Comprehensive DNA and RNA Sequencing Platforms with Subsequent Clinical Validation for Hematolymphoid Malignancies. [PDF]

Cancers (Basel)
Parlow JNC, Salcedo-Porras N, AlBulushi F, Yip S, McGinnis E, Spence T.   +5 more
europepmc   +1 more source

Cross Kingdom Metabolic Engineering Paradigm Elevating Sustainable Protein Production

Advanced Science, EarlyView.
ABSTRACT Confronting the dual crisis of escalating global protein demand and unsustainable agriculture necessitates transformative solutions. Here, we pioneer evolutionary insights from maize nitrogen optimization via asparagine synthetase (ASNS) to rewire metabolism in Pichia pastoris.
Yuanyuan Du, Changyu Pi, Kai Hong, Le Gao, Xin Wu   +4 more
wiley   +1 more source

Complete circular genome sequences representing prevalent sub-lineages of clinical <i>Listeria monocytogenes</i> isolates from Germany. [PDF]

Microbiol Resour Announc
Wamp S, Flieger A, Halbedel S.
europepmc   +1 more source

Multi‐Enzyme Mimetic Molybdenum Nitride Nanozymes Reshape Subgingival Microenvironment for Synergistic Periodontitis Therapy via ROS Regulation and Microbiome Remodeling

Advanced Science, EarlyView.
ABSTRACT Periodontitis, a chronic inflammatory disease initiated and sustained by plaque microorganisms and host immune response, remains an intractable oral disease and a leading cause of tooth loss worldwide. Traditional mechanical debridement and adjunctive antibiotic or antiseptic therapy often shows limited efficacy due to the complex anatomical ...
Weiyu Zhang, Zhongwei Yang, Yunfan Zhang, Longwei Wang, Xiaoyu Zhang, Jiahui Mao, Yizhi Dai, Yifan Yuan, Mingge Wang, Xin Yang, Xin Yu, Jing Liu, Chunying Chen   +12 more
wiley   +1 more source

P777: Genome sequencing detects transposable element (TE) insertions in two diagnostic challenging cases

Genetics in Medicine Open
Revathi Rajkumar, Anjana Chandrasekhar, Zinayida Schlachetzki, Samin Sajan, Brittany Thomas, Becky Milewski, Joshua Lowry, Richard Wang, Jon Albay, Danny Miller, Kaitlyn Burns, Laura Davis-Keppen, Nora Urraca, Kerri Bosfield, Katherine Cung, Erin Venti, Ryan Taft, Denise Perry, Akanchha Kesari   +18 more
doaj   +1 more source

Erratum: Single-neuron RNA-Seq: technical feasibility and reproducibility

Frontiers in Genetics, 2013
Shenfeng eQiu, Shujun eLuo, Oleg eEvgrafov, Robin eLi, Gary P Schroth, Pat eLevitt, James A Knowles, Kai eWang   +7 more
doaj   +1 more source

Choosing Between Short-Read 16S, Full-Length ONT 16S, and Long-Read Shotgun Metagenomics for Soil Microbiome Studies: A Critical Review of the Benchmarking Evidence. [PDF]

Microorganisms
Albastaki A, Smith J.
europepmc   +1 more source

A Radioresistant‐Tumor‐Targeted Nanoparticle for X‐Ray‐Controlled Nitric Oxide Release to Potentiate Radiotherapy

Advanced Science, EarlyView.
The PBTN targets GRP78 and, upon X‐ray irradiation, generates ONOO− to induce immunogenic cell death, thereby activating CD8+ T cells and establishing a systemic antitumor immune response. ABSTRACT Nitric oxide (NO) treated radioresistant tumors by relieving hypoxia and blocking DNA repair, but its nonselective toxicity has precluded therapeutic use ...
Wanze Zhang, Xiaoyan Yin, Ting Wang, Hongfu Zhao, Zhipeng Zhao, Jinbao Wang, Cheng Tao, Xuanchu Ge, Yanze Li, Linlin Liu, Fuxin Xue   +10 more
wiley   +1 more source

P636: Lp(a) genetic risk screening using genome sequencing

Genetics in Medicine Open
Samuel Strom, Laura Amendola, Aditi Chawla, Vitor Onucic, Denise Perry, Akanchha Kesari, Ryan Taft   +6 more
doaj   +1 more source