Results 61 to 70 of about 72,615 (261)

Development of a comprehensive cardiovascular disease genetic risk assessment test

Genetics in Medicine Open
Purpose: Despite monogenic and polygenic contributions to cardiovascular disease (CVD), genetic testing is not widely adopted, and current tests are limited by the breadth of surveyed conditions and variant interpretation burden.
Laura M. Amendola, Alison J. Coffey, Josh Lowry, James Avecilla, Alka Malhotra, Aditi Chawla, Stetson Thacker, Julie P. Taylor, Revathi Rajkumar, Carolyn M. Brown, Katie Golden-Grant, Rueben Hejja, Tasha Kalista, Jennifer A. Lee, Phillip Medrano, Becky Milewski, Felipe Mullen, Andrew Walker, Adriana Huertas-Vazquez, Mauro Longoni, Keisha Robinson, Denise L. Perry, Damon Hostin, Subramanian S. Ajay, Akanchha Kesari, Samuel P. Strom, Elliott Margulies, John Belmont, David E. Lanfear, Ryan J. Taft   +29 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Performance of a multi-species-plant illumina beadchip

, 2016
Since mid-2005, Illumina Infinium® genotyping arrays provide data with good accuracy for thousands of SNPs (single nucleotide polymorphism) in thousands individuals for many organisms including plants.
Boland-Auge, Anne, Chauveau, Aurelie, Faivre-Rampant, Patricia, Eggen, André, Le Paslier, Marie-Christine, Berard, Aurélie, Brunel, Dominique, Marquand, Elodie   +7 more
core   +2 more sources

Illumina sequencing.

, 2015
Descriptive statistics for the Illumina sequencing run and the assembly of the de novo transcriptomes.
Silvia Joly (820734), Francesco Lamanna (820731), Valerio Ketmaier (332293), Jacopo Aguzzi (244760), Valerio Sbragaglia (820730), Guiomar Rotllant (820733), Horacio O. de la Iglesia (165426), Audrey M. Mat (820732)   +7 more
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Single-neuron RNA-Seq: technical feasibility and reproducibility

Frontiers in Genetics, 2012
Understanding brain function involves improved knowledge about how the genome specifies such a large diversity of neuronal types. Transcriptome analysis of single neurons has been previously described using gene expression microarrays.
Shenfeng eQiu, Shujun eLuo, Oleg eEvgrafov, Robin eLi, Gary P Schroth, Pat eLevitt, James A Knowles, Kai eWang   +7 more
doaj   +1 more source

RNA-Seq Illumina

, 2020
RNA-Seq with ...
openaire   +2 more sources

Illumina reads for TA299

, 2021
<p>Raw Illumina short reads (~40x) for TA299 Triticum monococcum subsp.
Ibrahim Ahmed, Hanin
core   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

De Novo Genome Assemblies for Three North American Bumble Bee Species: Bombus bifarius, Bombus vancouverensis, and Bombus vosnesenskii

G3: Genes, Genomes, Genetics, 2020
Bumble bees are ecologically and economically important insect pollinators. Three abundant and widespread species in western North America, Bombus bifarius, Bombus vancouverensis, and Bombus vosnesenskii, have been the focus of substantial research ...
Sam D. Heraghty, John M. Sutton, Meaghan L. Pimsler, Janna L. Fierst, James P. Strange, Jeffrey D. Lozier   +5 more
doaj   +1 more source