Results 1 to 10 of about 94,759 (256)

Transcriptome profiling for precision cancer medicine using shallow nanopore cDNA sequencing

Scientific Reports, 2023
Transcriptome profiling is a mainstay of translational cancer research and is increasingly finding its way into precision oncology. While bulk RNA sequencing (RNA-seq) is widely available, high investment costs and long data return time are limiting ...
Andreas Mock, Melissa Braun, Claudia Scholl, Stefan Fröhling, Cihan Erkut   +4 more
doaj   +2 more sources

Addressing challenges in the production and analysis of illumina sequencing data

BMC Genomics, 2011
Advances in DNA sequencing technologies have made it possible to generate large amounts of sequence data very rapidly and at substantially lower cost than capillary sequencing.
Kelso Janet, Heyn Patricia, Kircher Martin   +2 more
doaj   +2 more sources

De Novo transcriptome assembly (NGS) of Curcuma longa L. rhizome reveals novel transcripts related to anticancer and antimalarial terpenoids. [PDF]

PLoS ONE, 2013
Herbal remedies are increasingly being recognised in recent years as alternative medicine for a number of diseases including cancer. Curcuma longa L., commonly known as turmeric is used as a culinary spice in India and in many Asian countries has been ...
Ramasamy S Annadurai, Ramprasad Neethiraj, Vasanthan Jayakumar, Anand C Damodaran, Sudha Narayana Rao, Mohan A V S K Katta, Sreeja Gopinathan, Santosh Prasad Sarma, Vanitha Senthilkumar, Vidya Niranjan, Ashok Gopinath, Raja C Mugasimangalam   +11 more
doaj   +2 more sources

Aspergillus sydowii: Genome Analysis and Characterization of Two Heterologous Expressed, Non-redundant Xylanases

Frontiers in Microbiology, 2020
A prerequisite for the transition toward a biobased economy is the identification and development of efficient enzymes for the usage of renewable resources as raw material.
Sophie C. Brandt, Bernhard Ellinger, Thuat van Nguyen, Sönke Harder, Hartmut Schlüter, Richard L. Hahnke, Martin Rühl, Wilhelm Schäfer, Martin Gand, Martin Gand   +9 more
doaj   +2 more sources

Next generation sequencing and de novo transcriptome analysis of Costus pictus D. Don, a non-model plant with potent anti-diabetic properties

BMC Genomics, 2012
Background Phyto-remedies for diabetic control are popular among patients with Type II Diabetes mellitus (DM), in addition to other diabetic control measures. A number of plant species are known to possess diabetic control properties.
Annadurai Ramasamy S, Jayakumar Vasanthan, Mugasimangalam Raja C, Katta Mohan AVSK, Anand Sanchita, Gopinathan Sreeja, Sarma Santosh, Fernandes Sunjay, Mullapudi Nandita, Murugesan S, Rao Sudha   +10 more
doaj   +2 more sources

Transcriptome of the Australian Mollusc Dicathais orbita Provides Insights into the Biosynthesis of Indoles and Choline Esters

Marine Drugs, 2016
Dicathais orbita is a mollusc of the Muricidae family and is well known for the production of the expensive dye Tyrian purple and its brominated precursors that have anticancer properties, in addition to choline esters with muscle-relaxing properties ...
Abdul Baten, Ajit Kumar Ngangbam, Daniel L. E. Waters, Kirsten Benkendorff   +3 more
doaj   +2 more sources

Systematic Comparison of Nanopore and Illumina Sequencing for the Detection of Plant Viruses and Viroids Using Total RNA Sequencing Approach

Frontiers in Microbiology, 2022
High-throughput sequencing (HTS) has become an important tool for plant virus detection and discovery. Nanopore sequencing has been rapidly developing in the recent years and offers new possibilities for fast diagnostic applications of HTS.
Ion Gutiérrez-aguirre, Adrian Fox, Neil Boonham   +2 more
exaly   +2 more sources

Review on Illumina Sequencing Technology

Austin Journal of Veterinary Science & Animal Husbandry, 2022
Illumina sequencing process utilizes biochemical methods to determine the correct order of nucleotide bases in a deoxyribonucleic acid. Macromolecule using sequencing-by-synthesis and reversible dye-terminators that enable the identification of single ...
Emiyu K, Lelisa K
semanticscholar   +1 more source

Electrode Microbial Communities Associated with Electron Donor Source Types in a Bioelectrochemical System Treating Azo-Dye Wastewater

Water, 2022
Bioelectrochemical systems (BESs) have been acknowledged to be an efficient technology for refractory pollution treatment. An electron donor is as an indispensable element of BES, and domestic wastewater (DW) has been proved as a cost-efficient and ...
Zechong Guo, Lufeng Zhang, Min-hua Cui, Aijie Wang   +3 more
semanticscholar   +1 more source

Shallow nanopore RNA sequencing enables transcriptome profiling for precision cancer medicine

bioRxiv, 2022
Transcriptome profiling is a mainstay of translational cancer research and is increasingly finding its way into precision oncology. While bulk RNA sequencing (RNA-seq) is widely available, high costs and long data return time are limiting factors for ...
A. Mock, Melissa Braun, C. Scholl, S. Fröhling, Cihan Erkut   +4 more
semanticscholar   +1 more source