Results 111 to 120 of about 43,261 (182)

A highly contiguous genome assembly for the wrentit (Chamaea fasciata), the sole representative of the babbler radiation in the Americas. [PDF]

J Hered
Benham PM, Cicero C, Burns KJ, Escalona M, Beraut E, Fairbairn CW, Seligmann WE, Marimuthu MPA, Nguyen O, Chumchim N, Toffelmier E, Nachman MW, Bowie RCK.   +12 more
europepmc   +1 more source

ERRα-KDM5C restrains STING enhancer activity to modulate type I interferon signaling in breast cancer progression. [PDF]

Cell Death Dis
Xu ZH, Chen J, He Y, Lei C, Wang XL, Huang DF, Li ZZ, Zhou H, Wang MY, Song CG, Lin J, Liu W, Wu XN, Zhang WJ.   +13 more
europepmc   +1 more source

Dual Action of Dipyridamole in Experimental Rheumatoid Arthritis: Suppression of Joint Inflammation and Upregulation of Muscle Anabolism via Adenosine and AMPK pathways

Arthritis &Rheumatology, Accepted Article.
Introduction Rheumatoid sarcopenia, characterized by the progressive loss of skeletal muscle mass and function, is a frequent comorbidity in rheumatoid arthritis (RA), linked to prolonged, severe systemic inflammation. Purinergic signaling (adenosine, AMP, and ATP) plays a crucial role in inflammation, myogenesis, and muscle hypertrophy.
Miguel Marco‐Bonilla, Maria Fresnadillo, Irene Sanchez‐Platero, Macarena de la Riva‐Bueno, Fernando Huete‐Toral, Gonzalo Carracedo, Carmen Conde, Yolanda Benitez, Pablo Minguez, Sandra Carolina Cifuentes, Joaquin Rams, Gabriel Herrero‐Beaumont, Raquel Largo, Aránzazu Mediero   +13 more
wiley   +1 more source

Multiplexed RNA imaging and <i>in situ</i> profiling in living cells. [PDF]

Chem Sci
Mi L, Khajouei S, You M.
europepmc   +1 more source

Dynamics of natural killer cell function upon recurrent stimulation

Biotechnology Progress, EarlyView.
Weekly stimulation of peripheral blood‐derived NK cells with engineered K562 feeder cells resulted in two distinct growth phases, shifting around Day 21–26. Cells in growth phase 2 exhibited slower growth, reduced metabolic activity, and lower cytotoxicity than cells from growth phase 1, which has implications for NK cell biomanufacturing.
Jennifer One, Janani Narayan, Frank Cichocki, Wei‐Shou Hu, Samira M. Azarin   +4 more
wiley   +1 more source

A near chromosome-level assembly of the serpentine endemic columbine, Aquilegia eximia. [PDF]

J Hered
Johns J, Escalona M, Miller C, Chumchim N, Nguyen O, Marimuthu MPA, Sacco S, Fairbairn C, Beraut E, Toffelmier E, Shaffer HB, Hodges S.   +11 more
europepmc   +1 more source

Sequential, chromosome‐specific glutamine synthetase double knockout with Cas‐CLOVER establishes enhanced CHO platforms for cell line development

Biotechnology Progress, EarlyView.
This study established the first creation of a commercially available double GS knockout (DKO) from a single KO in CHO‐K1 cells, called CleanCut GS CHO using Cas‐CLOVER. When combined with the Harbor‐IN transposase system, CleanCut GS CHO cells demonstrated a highly antibody productivity.
Cintia Gomez Limia, Valeriya Steffey, Hsueh Che Cheng, Daniel Machado, Thomas Hart, Mark Cameron McHargue, Corey Brizzee, Jack Crawford   +7 more
wiley   +1 more source

D-amino acid substitution and cyclization enhance the stability and antimicrobial activity of arginine-rich peptides. [PDF]

Microbiology (Reading)
Mendes B, Castelletto V, Hamley IW, Barrett G.   +3 more
europepmc   +1 more source

Inconsistent Transcriptomic Responses to Hexabromocyclododecane in Japanese Quail: A Comparative Analysis of Results From Four Different Study Designs

Environmental Toxicology and Chemistry, EarlyView.
Abstract Efforts to use transcriptomics for toxicity testing have classically relied on the assumption that chemicals consistently produce characteristic transcriptomic signatures that are reflective of their mechanism of action. However, the degree to which transcriptomic responses are conserved across different test methodologies has seldom been ...
Paul Béziers, Elena Legrand, Emily Boulanger, Niladri Basu, Jessica D. Ewald, Paula Henry, Markus Hecker, Jianguo Xia, Natalie Karouna‐Renier, Doug Crump, Jessica Head   +10 more
wiley   +1 more source

Use of DNA Methylation Profiling as a Molecular Classification Tool for Paediatric Central Nervous System Tumours: A Middle-Income Country Population-Based Study. [PDF]

Neuropathol Appl Neurobiol
Euzébio MF, Silva FLT, Hoffmann IL, Ruas JS, Kido LA, de Lima DG, Queiroz L, Cardinalli IA, Seidinger AL, Nascimento S, Tedeschi H, Puga RD, Sales PPZ, Jotta PY, Maschietto M.   +14 more
europepmc   +1 more source